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Three-in-one molecule shows promise in helping certain breast cancer patients
A newly designed three-part molecule could be the one answer patients with a certain form of breast cancer are looking for...
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CIS43 antibody prevents malaria in mice
Scientists have discovered a human antibody that protected mice from infection with the deadliest malaria parasite, Plasmodium falciparum...
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Experimental obesity drug prevents development of kidney stones
Scientists have found that a drug connected with fat regulation prevents the formation of kidney stones in mice...
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Extracellular vesicles could be personalised drug delivery vehicles
Researchers developed an approach and platform to create large amounts of fillable and targeted nanovesicles to deliver drugs to tumours in mice...
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Drug Target Review – Issue #1 2018
In this issue: how customised cell engineering advances immunotherapy, how insights into auto-immunity are providing new opportunities for immune-oncology, and advances in lab automation and robotics are accelerating the pace of antimicrobial therapy.
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Adaptive Designs in Clinical Trials 2018
In its 10th year, the Adaptive Designs in Clinical Trials conference returns to central London in April 2018...
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Change in neuron size could shed light on new treatments for ALS
Understanding how motor nerve cells respond to motor neurone disease could help researchers identify new treatment options...
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Pro72Arg gene variant increases tumour cell metabolism
Scientists have found a mechanism through which mutant p53 enhances metastasis by controlling tumour metabolism...
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Tempol provides a potential treatment for Chuvash polycythemia
A study in mice suggests that experimental drug may be effective against mountain sickness and other polycythemias...
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Scientists discover critical molecular biomarkers of preeclampsia
Small non-coding RNAs may be used to devise a diagnostic blood test for pregnant women...
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HIC1 protein may protect against intestinal disease
Scientists find molecular link between Vitamin A derivative and mouse intestinal health...
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VILPs stimulate human cells to produce insulin-like hormones
In an unexpected finding, scientists have identified four viruses that can produce insulin-like hormones that are active on human cells...
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Osimertinib resistance explained by computer simulations
Scientists have used molecular simulations to understand the resistance to osimertinib - an anticancer drug used to treat types of lung cancer...
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Huntington’s disease provides new cancer weapon
Scientists have discovered why Huntington's is so toxic to cancer cells and harnessed it for a novel approach to treat cancer...