First captured image of antigen-bound T-cell receptor at near-atomic resolution
Using cryo-electron microscopy, researchers have captured the structure of a membrane-bound T-cell receptor complex with bound antigen.
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Using cryo-electron microscopy, researchers have captured the structure of a membrane-bound T-cell receptor complex with bound antigen.
Researchers have developed a novel label-free method named tomographic phase microscopy in flow cytometry for measuring intracellular lipid droplets in 3D.
R&D Systems offers custom antibody production services to engineer the right antibody to solve your research question with confidence.
Single-domain antibodies (sdAb) are small, stable antibodies derived from camelids with a single monomeric variable domain.
27 July 2022 | By Molecular Devices & HeartBeat.bio
Watch this virtual panel discussion to identify ways to overcome common challenges in 3D biology research, regardless of where you are in your journey.
Researchers for the first time have captured images of an autoantibody bound to a nerve cell surface receptor, revealing the physical mechanism behind a neurological autoimmune disease.
Scientists have created a new imaging technique with graphene which generates clearer pictures of the structures of small molecules.
Listen along as experts explore some applications of microscopy in neuroscience and discuss common challenges and considerations.
Researchers have been using state-of-the-art microscopy to analyse bacteria’s shapeshifting behaviour, findings which could lead to treatments for UTIs.
A broader view of cellular processes during the drug discovery and development stages enabled by microscopy could help scientists to design better therapies for patients. In this interview, Drug Target Review’s Victoria Rees asks Dr Peter O’Toole, Head of Imaging and Cytometry at the University of York, UK about his…
In this exclusive Q&A, Drug Target Review’s Ria Kakkad spoke with Dr Michael Grange, Tomography Group Leader from the Rosalind Franklin Institute (RFI), UK about the advantages of using cryo-electron tomography imaging.
Antibiotic resistance is one of the key health challenges of the future. In a new study, researchers have carried out a multi-step analysis to deliver insights into translocation of the hydrophobic and hydrophilic portions of the large lipopolysaccharide molecules through the outer membrane of Neisseria gonorrhoeae. This article summarises their…
Here Bio-Rad presents the generation of specific anti-CAR T-cell antibodies to show how CAR T-cell analysis benefits from our modular antibody assembly technology using SpyTag-SpyCatcher protein ligation.
Dr Richard Goodwin, Head of Imaging & AI, Clinical Pharmacology & Safety Sciences at AstraZeneca, explores the latest innovation in early therapeutic development – spatial biology.
Researchers have developed a ground-breaking microscopy technique that allows proteins, DNA, and other tiny biological particles to be studied in their natural state in a completely new way.