news
Combination therapy prevails against BET inhibitor resistance
St. Jude Children's Research Hospital, US, scientists created a new combination therapy method to tackle drug resistance in a type of leukaemia with KMT2A gene rearrangement.
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Screening
video
Webinar: The Role of Neuronal Metabolism in Early Drug Discovery
Learning about the mitochondrial role in a neurodegenerative disorder.
news
Researchers develop screening model to evaluate potential cervical cancer drugs
Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.
article
Assay performance and the Z’-factor in HTS
Matthew Lloyd from the University of Bath reveals the importance of the Z-factor and Z’-factor in high-throughput screening, and how they can be used to determine assay performance, perform quality control on the screen, and identify active compounds.
article
De-risking drugs in multiplex assays before progressing to clinical trials
Sheraz Gul, Head of Assay Development and Drug Repurposing at the Fraunhofer Institute, discusses the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research to decrease the risk of potentially undesirable events in later clinical studies.
whitepaper
Application note: Revolutionising drug formulations with polysorbate detection
Transform your drug manufacturing process with the latest breakthroughs in technology. Effortlessly identify and differentiate degradation components of PS20 in protein-containing samples.
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Drug Target Review Assays ebook 2023
Download your FREE ebook on assays, featuring articles from experts who write about developments in screening and the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research.
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Drug Target Review – Issue 1 2023
A new Drug Target Review is now ready to download! This issue features articles which explore antibodies, vaccines and assays.
whitepaper
Whitepaper: PSMA Protein in the Battle Against Cancer
The PSMA Protein is a new therapeutic hot target. In this article, learn about its growing role in the fight against prostate cancer and beyond.
webinar
Accelerating hit finding programs: Echo MS and RapidFire-MS key advantages
16 March 2023 | By Eurofins Discovery Services
In this on-demand webinar, we present the most advanced label-free technologies in identifying successful hit series for Hit-to-Lead and Lead-Optimization programs.
video
Webinar: Accurate detection of mitochondrial toxicity
Using Agilent Seahorse XF technology with the XF Mito Tox Assay allows for streamlined, reliable identification of mitochondrial toxicants.
video
Video: Spatial imaging as a tool for discovery
Watch Dr David Rimm from the Yale School of Medicine talk about his recent work and take on the future of multiplex spatial profiling of the TME.
whitepaper
Application note: Developing next-gen in vitro Huntington’s disease assays
The use of high-density MEAs to probe single cell and network activity electrophysiology of a hiPSC-derived Huntington’s disease model
whitepaper
Whitepaper: Cell cycle and DNA damage and repair
Explore pathways of cell cycle control, revealing mechanisms of cell cycle arrest, DNA damage and senescence using this ebook.
whitepaper
Whitepaper: Mitochondrial toxicity assessment
This whitepaper establishes a customised XF assay solution for the detection of mitochondrial toxicity using standardised parameters.