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6 April 2017 | By Niamh Marriott (Drug Target Review)
In a Phase I clinical trial, heart failure patients treated with patches made from their muscle cells showed improved exercise capacity and heart function after one year. Stem cell patch-based therapy may be a viable heart failure therapy and should be validated in larger clinical trials, researchers conclude.
3 April 2017 | By Niamh Marriott (Drug Target Review)
Researchers from UPM and CSIC have employed waste from the agri-food industry to develop biomaterials that are able to act as matrices to regenerate bone and cartilage tissues, which is of great interest for the treatment of diseases related to ageing.
31 March 2017 | By Niamh Marriott (Drug Target Review)
Plasticell, a developer of stem cell technologies and cell-based therapies, has signed agreements with the Agency for Science, Technology and Research (A*STAR) and the Nanyang Technological University (NTU) to progress its therapeutic stem cell pipeline.
29 March 2017 | By Steve Bremer (Drug Target Review)
Researchers have shed light on genome reorganisation occurring during the first hours post-fertilisation in a single-cell mammalian embryo
28 March 2017 | By Niamh Marriott (Drug Target Review)
A new study has found that stem cell therapy can reduce lung inflammation in an animal model of chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Although, still at a pre-clinical stage, these findings have important potential implications for the future treatment of patients.
17 March 2017 | By Niamh Marriott (Drug Target Review)
Envigo is helping to define the non-animal technologies regulatory environment, with its scientists currently sitting on OECD expert working groups...
15 March 2017 | By Niamh Marriott (Drug Target Review)
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
10 March 2017 | By University of Nashville
Research in zebrafish opens up new ideas for therapies for blinding diseases
9 March 2017 | By University of Tsukuba
KL4 could improve efficiency in stem cell generation
9 March 2017 | By Salford University
Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to an article published in Oncotarget
The growth-arrest specific 6 (GAS6) protein has emerged in recent years as an attractive target for drug development primarily because it is the sole ligand for the AXL receptor tyrosine kinase, which plays critical roles in cancer, fibrosis, and viral infection.
2 March 2017 | By Niamh Marriott (Drug Target Review)
How do tumours grow? And how do bacteria transform harmless substances into medical agents? When biophysicists want to understand what is happening in living cells, they have to introduce fluorescent probes or other foreign molecules. There are several ways to overcome the cell wall without causing the cell permanent harm.
28 February 2017 | By Niamh Marriott (Drug Target Review)
Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.