Application note: Improving High Throughput AlphaLISA® with The TEMPEST®
Using TEMPEST®, St. Jude Children’s Research Hospital were able to rapidly screen a focused compound library for early cancer drug candidates in an AlphaLISA® assay.
Using the TEMPEST® liquid handler from Formulatrix, and in collaboration with HighRes Biosolutions® for integration of the instrument with an existing automation platform, researchers at St. Jude Children’s Research Hospital were able to rapidly screen a focused compound library screening early cancer drug candidates in an AlphaLISA® assay. The success of this project was facilitated by a number of key TEMPEST® features, namely an in-built capacity to recirculate the AlphaLISA® beads, the ability to dispense multiple reagents from a single dispenser, and extremely low dead volumes.
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Analytical techniques, Antibodies, Antimicrobials, Assays, Bioengineering, Biomarkers, Biopharmaceuticals, Cell culture, Disease research, Genome editing, Hit-to-Lead, Immunology, Informatics, Lab Automation, Label-free, Lipidomics, Mass Spectrometry, Personalised Medicine, Proteomics, Regenerative Medicine, Screening, Sequencing, Spectroscopy, Stem Cells, Targets, toxicology