All Assays articles – Page 11
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VideoVideo: Using luciferase reporter cell lines for HTS readouts
This video reviews the uses and advantages of reporter cell lines in the context of cellular research and drug discovery.
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WebinarNormalization of organ-on-a-chip samples for mass spectrometry based proteomics and metabolomics via dansylation-based assay
A discussion of the recently published paper, “Normalization of Organ-on-a-Chip Samples for Mass Spectrometry Based Proteomics and Metabolomics via Dansylation-based Assay,” and how the field can produce more replicable experiments.
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Whitepaperebook: Quantitative Assays to Measure Ab Binding to Fc Receptors
This ebook summarizes the basics of Fc receptor function and discusses biochemical and cell-based assays that enable antibody optimization projects.
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Whitepaperebook: TR-FRET assay kits simplify & accelerate drug discovery
This ebook provides basic principles of the TR-FRET technology and shows examples of how assay design can drive drug discovery.
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WebinarAccelerating biologics discovery via antibody library and reaching IND faster with cell line development
The application of Fab and VHH naïve library to expedite the antibody discovery against tumor-associated antigen for CAR-T, ADC and bispecific antibody.
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VideoWebinar: The Role of Neuronal Metabolism in Early Drug Discovery
Learning about the mitochondrial role in a neurodegenerative disorder.
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Article
Assay performance and the Z’-factor in HTS
Matthew Lloyd from the University of Bath reveals the importance of the Z-factor and Z’-factor in high-throughput screening, and how they can be used to determine assay performance, perform quality control on the screen, and identify active compounds.
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ArticleDe-risking drugs in multiplex assays before progressing to clinical trials
Sheraz Gul, Head of Assay Development and Drug Repurposing at the Fraunhofer Institute, discusses the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research to decrease the risk of potentially undesirable events in later clinical studies.
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WhitepaperApplication note: Revolutionising drug formulations with polysorbate detection
Transform your drug manufacturing process with the latest breakthroughs in technology. Effortlessly identify and differentiate degradation components of PS20 in protein-containing samples.
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ArticleDrug Target Review Assays ebook 2023
Download your FREE ebook on assays, featuring articles from experts who write about developments in screening and the importance of performing comprehensive multiplex spatial and temporal profiling of drugs in pre-clinical research.
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WhitepaperApplication note: Single Cell Deposition Efficiency
Comparison of single cell dispensing efficiency between Namocell Single Cell Dispenser and limiting dilution method.
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WhitepaperWhitepaper: PSMA Protein in the Battle Against Cancer
The PSMA Protein is a new therapeutic hot target. In this article, learn about its growing role in the fight against prostate cancer and beyond.
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WebinarAccelerating hit finding programs: Echo MS and RapidFire-MS key advantages
In this on-demand webinar, we present the most advanced label-free technologies in identifying successful hit series for Hit-to-Lead and Lead-Optimization programs.
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WhitepaperGuide: Tips for Single Cell Isolation
Single cell isolation is a critical step for a number of workflows, and can greatly impact the success of downstream applications.
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WhitepaperApplication note: Generating clonal GFP cell lines
Namocell single cell dispensers use gentle sorting pressure to isolate and dispense GFP-positive cells into 96-well plates.
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VideoWebinar: Accurate detection of mitochondrial toxicity
Using Agilent Seahorse XF technology with the XF Mito Tox Assay allows for streamlined, reliable identification of mitochondrial toxicants.
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WhitepaperApplication note: Enrichment of high titer CHO clones
A selective FACS-enrichment was performed via the enrichment mode of Namocell Single Cell Dispenser to enrich for high titer CHO cells.
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VideoVideo: Spatial imaging as a tool for discovery
Watch Dr David Rimm from the Yale School of Medicine talk about his recent work and take on the future of multiplex spatial profiling of the TME.
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WhitepaperApplication note: Developing next-gen in vitro Huntington’s disease assays
The use of high-density MEAs to probe single cell and network activity electrophysiology of a hiPSC-derived Huntington’s disease model
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ArticleEpisode 17 – Imaging: data analysis of organoids
Tune into this podcast to hear experts discuss imaging and analysing data from organoids!