All Genomics & Sequencing articles – Page 10
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NewsNew study uncovers DNA repair mechanism in bacterial cells
US research reveals mechanism used by bacterial cells to repair their faulty DNA, which could help scientists understand the intricacies of DNA repair processes.
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NewsComputational tool gets more out of multi-omics data
US researchers developed a next-generation computational tool called NetBID2 that can uncover difficult-to-identify proteins that drive biological processes contributing to cancer.
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ArticleCRISPR and single-cell sequencing highlight genetic variants for traits and diseases
This article highlights a new approach to address human genetics, using STING-seq which provides roadmap to identify variants and genes, enabling deeper understanding of the noncoding genome and targets for therapies
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NewsBlocking a microRNA may prevent age-related conditions
Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
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NewsNew treatment pathway for deadly pancreatic cancers
US scientists have used mouse models of pancreatic cancer to identify genes used by tumour cells to grow uncontrollably.
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NewsAntimicrobial resistance identified in bloodstream by metagenomic sequencing
University of Oxford finds rapid metagenomics can produce accurate results 18-42 hours quicker than conventional tests for antimicrobial resistance in bloodstream infections, which could save lives and reduce the misuse of antibiotics.
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NewsNew class of ribosomal peptide "daptides" discovered by researchers
Researchers from the University of Illinois have identified a new class of ribosomally synthesised and post-translationally modified peptides (RiPPs) named "daptides" that have haemolytic activity.
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NewsNew organoid emulates development of the human heart
The team are the first researchers in the world to successfully create an organoid containing both heart muscle cells and cells of the outer layer of the heart wall.
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NewsAnalysis of 33 tumour types identifies new immunotherapy targets
The researchers identified 1,068 transposable element-derived transcripts with the potential to produce tumour antigens that could serve as targets for new immunotherapies.
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NewsMouse study at USC reveals why leukemic mutation varies
A mechanism linked to a genetic mutation could help identify patients who are at higher risk of developing leukaemia.
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NewsNew genes modulate toxicity of the protein that causes Alzheimer’s
Scientists from Spain have identified genes that regulate Alzheimer’s disease, including Surf4, which alters the regulation of calcium within Alzheimer’s cells.
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NewsFirst molecular therapeutic for Angelman syndrome to advance into clinical trials
The scientists from Texas A&M have developed GTX-102, a novel therapeutic candidate to target Angelman syndrome by reactivating expression of deficient protein.
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Researchers find ancient virus genome drives autism
The scientists revealed in mice models that endogenous retrovirus activation increases a foetus’s susceptibility to autism.
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NewsResearch shows lipid nanoparticles are highly effective in gene therapy
Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.
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NewsResearchers develop organoid models to study non-alcoholic fatty liver disease
The team used these models to show drug responses and established a CRISPR-screening platform to identify potential therapeutic targets for non-alcoholic fatty liver disease.
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NewsThe future for quality control of mRNA medications
Japanese researchers combine cutting edge mass spectrometry with software analysis to elucidate mRNA structure.
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NewsWhat do cancer cells crave?
US researchers uncover the amino acid: arginine, that prompts genetic mutations in cancer cells.
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NewsWhat is the link between serotonin and heart valve disease?
US researchers found that serotonin impacts the mitral valve in the heart which can lead to heart valve disease.
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WebinarUsing integrative biophysical approaches to understand GPCR regulation by β-arrestins
Watch this webinar to learn how an integrated structural biology workflow can be used to get crucial structural insights on key protein targets that are of therapeutic interest.
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NewsResearchers develop novel method to insert large DNA sequences more accurately in cells
The scientists say that the engineered CRISPR enzymes could overcome key limitations for eventual use to treat genetic diseases irrespective of a patient’s particular mutation.