All Karolinska Institutet articles
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ArticleBeyond weight loss: the gap in current drug development for obesity
Current obesity drug development remains overly focused on short-term weight reduction, despite obesity being a chronic, multifactorial disease. Broader, mechanism-driven approaches are needed to ensure durable efficacy, safety and accessibility.
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NewsNew AI algorithm searches 10 sextillion drug candidates
Scientists have developed an AI algorithm capable of searching through 10 sextillion potential drug molecules, a feat previously considered impossible. This method could significantly speed up drug discovery and the development of new treatments.
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NewsDetermining the cellular architecture of multiple sclerosis lesions
Using in situ sequencing, a collaborative research group analysed 260 genes and discovered new sub-structures in MS lesions.
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NewsNasal administration of IgA antibodies protects from SARS-CoV-2
Genetic engineering created IgA antibodies that bind to the SARS-CoV-2 spike protein in a similar way to IgG antibodies.
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News
Metabolic change in hippocampus indicates Alzheimer's disease
Using RNA sequencing, scientists find that metabolic increase in the brain is an early indicator of Alzheimer's disease.
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NewsHarnessing machine learning for early cancer detection in primary care
Machine learning (ML) presents a promising opportunity to revolutionize early cancer detection in primary care, addressing the challenges associated with diagnostic errors and improving patient outcomes. The potential of ML in this field is highlighted in a recent paper published in Oncoscience
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NewsNew immunotherapy approach holds promise for ovarian cancer
A new approach using CAR T-cell therapy is suggested by Swedish researchers as an effective treatment for ovarian cancer.
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NewsNew database maps proteins that could predict cancer
Swedish researchers unveiled a new cancer protein profile database compiled from artificial intelligence and machine learning.