All Metabolic disorders articles – Page 5
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NewsDeveloping precision medicine for gestational diabetes
Researchers have identified that gestational diabetes is associated with a deficit in placental expression of IGFBP1.
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NewsRare genetic variants found to have a large impact on obesity risk
Researchers have gained a deeper understanding of the neural biology of obesity, which could offer potential drug targets.
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NewsScientists elucidate the mechanism behind middle-aged obesity
New findings show that age-related MC4R+ cilia shortening causes middle-aged obesity and leptin resistance, which could lead to obesity treatment.
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NewsUncovering the bidirectional relationship between PD and DM
Single-cell RNA analysis provides an immunological explanation for the association between periodontitis and diabetes mellitus.
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NewsImproving treatments for rheumatoid arthritis patients
Researchers found that resolvinT4 restores protective macrophage biological activities in rheumatoid arthritis patients.
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NewsAdvantages of using cfDNA sequencing for early detection of GDM
A deep learning model developed using circulating cell-free DNA outperformed traditional screening methods for gestational diabetes mellitus.
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ArticleHow AI is accelerating the future of precision medicine
Dr Ketan Patel, Clarivate, shares his insights about the use of Real-World Data and genomic biomarker data and discusses how researchers can use these to better detect and diagnose diseases.
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NewsPotential of precision diagnostics for gestational diabetes mellitus
Researchers highlight the need for a more nuanced diagnostic approach, examining whether nonglycemic markers could refine risk stratification.
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ArticleNew biomarkers found for diabetic kidney disease
Biomarkers found through urinary and exosome proteome profiling have potential for diagnosis and disease monitoring.
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NewsNew potential drug target is discovered for diabetes treatment
Researchers found heightened SCAN enzyme activity in humans and mice with diabetes results in excessive nitric oxide on insulin receptors.
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NewsMutated DECTIN-1 and its implications for autoimmune disease
A discovery about the mutated protein DECTIN-1, that limits the production of T regulatory cells, could lead to more effective drugs.
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Biomarkers found in the temporary regression of type 1 diabetes
The partial remission phase of type 1 diabetes, in which residual β-cells recover insulin production, offers new hope for therapeutic action.
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ArticleHuman organoid research offers insights into gut cell differentiation
How stem cells become enteroendocrine cells using gut organoids could have positive implications for many gastrointestinal diseases.
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NewsDirect link between hyperinsulinemia and pancreatic cancer found
Excessive insulin levels in people with obesity and type 2 diabetes overstimulates pancreatic cells, initiating disease.
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NewsStudy reveals harmful gut bacteria linked to irregular sleep patterns
New Study from King's College London: Irregular Sleep Patterns Tied to Harmful Gut Bacteria.
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Unlocking the achilles' heel of insulin pump technology
Study led by UW Medicine reveals concerns about insulin pump therapy for type 1 diabetes patients. Long-term pump usage can lead to fibrotic, irritated infusion sites, making insulin delivery less effective
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NewsAre female mice better protected against obesity?
The University of California underwent a mouse study disclosing underlying sex differences in mice for obesity.
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NewsHow do cells control the secretion of mucin and insulin?
Spanish researchers looking at two crucial proteins uncover how cells release mucin and insulin, leading to new methods to reset deregulation.
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NewsNew algorithm can predict diabetic kidney disease
Researchers from US and Hong Kong have found that a simple blood sample may help doctors catch kidney disease earlier in type 2 diabetes patients
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NewsCancer-killing benefits of popular obesity treatment
Findings from the Republic of Ireland, in relation to GLP-1 obesity treatment showcase its ability to restore the body’s natural cancer-killing defences.