Technology – Page 15
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ArticleUnleashing the power of AI in target discovery and resilience against disease
In this interview Drug Target Review’s Izzy Wood and Olivia Cavlan, Chief Corporate Development and Strategy Officer at Alchemab Therapeutics Ltd, uncover the untapped potential of AI in target discovery. Alchemab’s revolutionary platform aims to identify common antibodies in resilient individuals and uncover the antigens that contribute to their disease-fighting ...
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ArticleEpigenetic editing: the next generation of genetic medicine
Dr Blythe Sather at Tune Therapeutics reveals why epigenetic editing offers benefits above and beyond those of gene editing, potentially bridging the gaps to breakthroughs in the clinic.
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ArticleExploring alternatives to animal testing in drug discovery
The use of animal studies in drug development has become a growing ethical concern, particularly given the high failure rate of clinical trials, which can reach up to 90 percent. This article highlights non-animal models that could expedite the drug delivery process from bench to bedside.
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ArticleMore than just a microscope: how advanced imaging modalities can take your pharmaceutical research to the next level
When you think of microscopy for drug discovery, you may picture images of fixed cells or histologically stained sections of biopsies, collected long after a drug has taken effect. Instead, imagine watching drug responses in real time in whole living animals, visualising drug delivery vehicles at nanoscale and removing the ...
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ArticleAdvancing directed protein evolution technology
Drug Target Review's Ria Kakkad spoke with Victoria Goldenshtein at PEGs Europe, about her lab’s novel in vitro library display platform for directed protein evolution called GRIP display – gluing RNA to its proteins.
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ArticleKey considerations before commencing cell line development
Cell line development (CLD) is a critical, early step when entering the development phase of a biotherapeutic. Access to specialist skills and experience, either in-house or remotely, and to multiple technologies and equipment can prove invaluable for the timely and successful completion of this stage. Here, Dr Alison Porter addresses ...
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ArticleThe power of single-cell technologies
Drug Target Review’s Taylor Mixides interviews Cellarity's CEO Fabrice Chouraqui about applying Artificial Intelligence (AI) and Machine Learning (ML) to evolving single-cell technologies.
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ArticleNext-generation CAR T cells
Dr John Maher discusses the challenges associated with developing chimeric antigen receptor (CAR) T-cell therapy for solid tumours.
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ArticleAdvancing gene editing to redefine therapies across genetic disease
In the unmet need for effective treatments to alleviate suffering and prevent premature death across the spectrum of genetic diseases, Brent Warner, Poseida Therapeutics, shares that the ability to edit DNA holds hope for patients currently experiencing incurable genetic diseases and has spurred ongoing efforts to develop and improve gene ...
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ArticleThe evolution and promise of gene therapies
Dr David Baram from gene therapy company EmendoBio provides a snapshot of the history of therapeutic genetic engineering.
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ArticleWomen in STEM with Dr Jo Brewer
Come and join us for our monthly series highlighting Women in STEM. We are excited to present the latest edition for June, featuring an exclusive interview with Dr Jo Brewer, Chief Scientific Officer at Adaptimmune. With a remarkable 15-years of experience in cell therapy, Jo's passion for cells has been ...
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ArticleThe role of CRISPR in microbiome engineering breakthroughs
Dr Jakob Krause Habber and Dr Richard Fox will explore the applications of CRISPR in microbiome engineering and how it can be used to overcome the bottleneck of human microbiome research.
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ArticleDrug Target Review Imaging eBook
In this eBook, explore how cutting-edge imaging modalities can elevate your biomedical research.
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ArticleDrug Target Review Screening eBook 2023
In this eBook, uncover the transformative potential of AI/ML in single-cell technologies and gain insights into disease progression.
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ArticleDrug Target Review Cell and Gene Therapy eBook 2023
Download your FREE ebook, featuring articles about cancer therapies, immune system breakthroughs, therapeutic genetic engineering, and advancements in gene editing.
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ArticleDrug Target Review - Issue 2 2023
A new Drug Target Review issue is now ready to download! This issue features articles on cell and gene therapy, imaging and screening.
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ArticleThe genetic modifier approach: identifying the right target for rare diseases
In this article, Dr Vincent Blomen, Senior Director of Target Discovery at Scenic Biotech, takes us through the realm of rare diseases. In the case of most of these diseases, a singular genetic anomaly often reigns supreme, yet its impact on patients can be vastly divergent. Enter modifier genes, the ...
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VideoVideo: Four integrated technologies for biologics developability assessment
The decisions you make about your biologics candidates early in the pipeline ultimately affect their success as therapeutics. Combine sizing and stability information to develop successful biologics.
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Articleebook: Breaking Barriers in Cell Engineering
Download this FREE ebook now and explore single-cell analysis, unlocking the secrets of therapeutic efficacy and safety. Immerse yourself in exclusive content, including cutting-edge cell line development articles and riveting interviews with industry experts. Don't miss your chance to discover the future of cellular therapies – start your journey today!
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ArticleGame-changing pan-TEAD inhibitor for solid tumours
Insilico Medicine has announced the nomination of ISM6331 as a potential best-in-class pan-TEAD inhibitor for the treatment of advanced solid tumours.