All Chimeric Antigen Receptors (CARs) articles – Page 2
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NewsFOXO1 improves survival and function of CAR T cells
Evidence indicating that FOXO1 plays a unique role in promoting T cell longevity could result in more effective CAR T cell therapies.
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NewsNew strategies to overcome CAR T-cell resistance in AML cells
Pharmacological concomitant therapies or further genetic improvement of CAR T-cells can increase their effectiveness against TP53-mutant AML cells.
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ArticleInsights into cellular therapies for cancer treatment
Many exciting developments are expected to take place in immunotherapy and oncology in the next few years. We had the privilege of discussing the opportunities of various cell therapies with Dr Suresh Nair, Physician in Chief, who elucidates how Lehigh Valley Topper Cancer Institute is directing research towards better treatments, ...
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News
Improved CAR T-cell immunotherapy for acute myeloid leukaemia
Researchers have created dual-targeted CARs, which performed better than single-targeted CARs in both in vivo and in vitro experiments.
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WhitepaperArticle: Tips and Tricks for Leveraging Advanced Flow Cytometry
Tips and tricks for fully leveraging Advanced Flow Cytometry.
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WhitepaperHandbook: Advanced flow cytometry handbook
Don’t miss out on the easier way to do flow cytometry. Learn how to bring speed, throughput, multiplexing and miniaturization, to your bench.
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News
Utilising CAAR T cells to treat antibody-caused brain disease
Researchers have engineered CAAR T cells to destroy harmful antibodies, improving NMDA receptor encephalitis treatment.
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NewsMachine could make CAR T-cell therapy more accessible
Researchers have developed a new bioreactor that can manufacture T cells faster than other technologies, which may advance immunotherapy.
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NewsKey epitope can trigger tumour cell death
An epitope on CD95 receptor causes tumour cells to self-destruct and may prolong benefits of CAR T-cell therapy for solid tumours.
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NewsCancer-killing T cells enhanced by engineered bacteria
Bacteria programmed to paint targets on solid tumours for T cells to see eliminates the need for specific antigens.
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WebinarComplete aggregate and particle characterisation of protein, gene and cell therapies
Join us to learn about the importance of subvisible particle characterisation for better product stability, ensuring patient safety from early-phase development through USP 788 lot release testing.
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WebinarComplete CAR-T workflow solutions for research
Watch this webinar to get an overview of the CAR-T workflow and learn about the latest CAR-T research enabling tools that can accelerate your discovery.
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ArticleNext-generation CAR T cells
Dr John Maher discusses the challenges associated with developing chimeric antigen receptor (CAR) T-cell therapy for solid tumours.
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ArticleDrug Target Review Cell and Gene Therapy eBook 2023
Download your FREE ebook, featuring articles about cancer therapies, immune system breakthroughs, therapeutic genetic engineering, and advancements in gene editing.
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ArticleDrug Target Review - Issue 2 2023
A new Drug Target Review issue is now ready to download! This issue features articles on cell and gene therapy, imaging and screening.
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NewsCustomising T cell-based immunotherapies to treat cancers
US researchers usings a ‘SNAP’ receptor system can customise immunotherapies for targeted treatments of cancer and other diseases.
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WebinarAccelerating biologics discovery via antibody library and reaching IND faster with cell line development
The application of Fab and VHH naïve library to expedite the antibody discovery against tumor-associated antigen for CAR-T, ADC and bispecific antibody.
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NewsWhat is the key source of T cell exhaustion?
US discovery opens the way to drugs that can prevent T cell therapies from losing their potency over time.
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NewsImproving immunotherapy against brain cancer
US scientists suggest that anti-angiogenesis drugs could improve the function and delivery of CAR-T cell therapy.
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NewsNew immunotherapy approach holds promise for ovarian cancer
A new approach using CAR T-cell therapy is suggested by Swedish researchers as an effective treatment for ovarian cancer.
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