All Gene Therapy articles – Page 6
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ArticleCould scratching nerve cells be the itch solution?
The sensation of itch is something everyone has experienced at some point in their lives. It's a natural response to various irritants, from insect bites to dry skin. But what happens when the urge to itch becomes relentless, causing discomfort and, in some cases, serious health problems?
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NewsSCID-X1 gene therapy successful with 3D genome architecture
New research improves patient care by finding where gene copies integrate into DNA and using lentiviral vectors.
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NewsChildhood cancer survivors’ mortality risk
Researchers find genetic explanation for increased risk of developing second cancers.
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Explosive cell death: inflammation-causing gene
WEHI researchers have found that a genetic change of MLKL increases risk of uncontrolled inflammatory response
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WebinarComplete aggregate and particle characterisation of protein, gene and cell therapies
Join us to learn about the importance of subvisible particle characterisation for better product stability, ensuring patient safety from early-phase development through USP 788 lot release testing.
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NewsProteolysis: new method developed to target cancer cells
Researchers have found that targeting chimeras with click-release proteolysis activates specific molecules that target cancer cells without harming health cells.
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ArticleWomen in Stem with Dr Emily Leproust
This September edition of our Women in Stem series spotlights Dr Emily Leproust, CEO of Twist Bioscience. Dr Leproust began her STEM journey from a background in chemistry, eventually leading her to the forefront of DNA synthesis technology. She co-founded Twist Bioscience in 2013, now a thriving company reporting substantial ...
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Advancing obesity and diabetes therapy with brown fat cells
Researchers discover the intricate cellular signalling cues that orchestrate the formation of brown adipocytes in mice.
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ArticleScientists target protein in skeletal muscle composition
A group of researchers from Tokyo Metropolitan University have illuminated a crucial piece of the intricate puzzle surrounding the regulation of muscle mass and metabolic processes within skeletal muscle.
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Newly identified cell type uncovered in the thymus
Microfold cells (M cells) are primarily known for their role in the intestinal epithelium. However, the researchers discovered similar cells in the thymus.
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NewsVaccines against parasitic disease
In Columbus, Ohio, scientists have made significant strides in developing vaccines to combat leishmaniasis, a disfiguring skin disease, through animal studies.
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NewsDectin-1: HIV and ageing
New study aimed to assess how Dectin-1 functions in myeloid cells among various cohorts of individuals.
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NewsModified neural stem cells for spinal cord injury
Using genetically modified human neural stem cells (hNSCs), researchers demonstrated that targeted manipulation of a specific gene expression within hNSCs can facilitate the restoration of damaged neural circuits and recovery of locomotor functions.
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ArticleHuntington's disease and potential therapies
In this exclusive interview with Young Kwon, CEO of Alchemab, we discuss new platforms that are revolutionising how researchers identify naturally occurring antibodies in resilient individuals, opening up new possibilities for the development of disease-modifying therapies.
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ArticleHPV-associated head and neck cancers identified
Human papillomavirus (HPV)-associated head and neck cancers, specifically head and neck squamous cell carcinoma (HNSCC), are on the rise worldwide. Yet, the factors contributing to these tumours and their varying responses to treatment remain poorly understood.
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NewsNeuronal relocation facilitates healthy retina formation
During embryogenesis, organs must achieve a precise cell count and functional structure. Embryos efficiently manage multiple tasks—growth, shaping, and architecture establishment. Despite extensive research on embryonic development, the intricate coordination of these tasks in both space and time remains incompletely understood.
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ArticleAgeing and cancer-causing gene: researchers uncover a link
Researchers from UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine have made a discovery linking the notorious cancer-causing gene, Myc, to the process of ageing.
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NewsSickle cell anaemia: gene therapy insights for blood disorders
Cutting-edge research conducted by experts at Michigan Medicine, the Children’s Hospital of Philadelphia, and Penn Medicine is revolutionising the approach to treating blood disorders like sickle cell anaemia through innovative gene therapy methods.
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ArticleCancer metastasis: breakthrough in therapeutic strategies
A new discovery from the University of Southern California (USC) on cancer metastasis has opened up new possibilities for combating the spread of this devastating disease.
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ReportBeyond the lab: cell & gene therapy
The launch of our new series, "Beyond the Lab," promises to deliver high-level insights commissioned exclusively by Drug Target Review magazine. Our inaugural report is an exploration of the remarkable advancements in cell and gene therapy that are revolutionising the field of drug discovery.