All Protein Expression articles – Page 6
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NewsPotential therapeutic target for ventricular fibrillation found
A signalling mechanism for ventricular fibrillation involving the stress kinases p38γ and p38δ has been discovered.
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NewsNew algorithm identifies a novel CRISPR-Cas system
Findings of rare CRISPR-linked gene modules and a novel CRISPR-Cas system have promising implications for genomic therapeutics.
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WhitepaperApplication note: Next-gen protein sequencing rapid ID of COVID variants
Quantum-Si's Next-Generation Protein Sequencing technology on Platinum™, rapidly distinguishes SARS-CoV-2 variants based on amino acid sequence.
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NewsNano-sized traps enable better study of proteins
Researchers have developed a new method to study protein clumps that occur in many difficult-to-treat diseases.
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WhitepaperApplication note: Solutions for your protein sample preparation workflow challenges
Researchers often encounter common problems during protein sample preparation which can compromise the quality and quantity of protein obtained. Explore our solutions to these common challenges, including sample handling, storage and preparation method issues.
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NewsEssential role of Nrg1 in heart development
New research identifies how trabeculae transform into ventricles, which could positively impact heart disease treatments.
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ArticleHow a dynein subunit maintains neuronal health
Understanding how a molecular transport system inside neurons works could be used for therapeutic approaches to neurodegenerative disease.
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ArticleUnderstanding intracellular processes improves LYTACs therapy
New pathway involved in cellular protein degradation could develop LYTACs therapy and find new treatments for lysosome shortage disorders.
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ArticleProtein offers promise for treatment of reproductive conditions
Scientists found that CXCR4 protein expression outside of the uterus is important for pregnancy maintenance.
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WebinarBiophysical characterisation of binary and ternary drug-target complexes using the BRUKER SPR-32 PRO platform
Gain comprehensive insights into screening potential drugs, manipulating drug targets at the molecular level and employing techniques like SPR and X-ray crystallography for studying molecular interactions.
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WebinarComplete aggregate and particle characterisation of protein, gene and cell therapies
Join us to learn about the importance of subvisible particle characterisation for better product stability, ensuring patient safety from early-phase development through USP 788 lot release testing.
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WhitepaperGuide: Screening biologic candidates with nanoDSF
Read this guide about nanoDSF for high-resolution measurements of thermal stability parameters, common CQAs for biologics developability assessment.
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WhitepaperInfographic: Biologics stability in early development
Stability attributes of biologic candidates are evaluated during early development workflows. Learn how to measure them with biophysical techniques.
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News
Protein-triggered motor neuron loss in amyotrophic lateral sclerosis
The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the cerebral cortex to motor neurons in the spinal cord, which in turn activate muscles, enabling fluid motion. ...
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NewsMSK1’s importance for cognitive benefits
New study uncovers role of a neuronal protein kinase called mitogen- and stress-activated protein kinase 1 (MSK1) in mediating the cognitive benefits of environmental enrichment.
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NewsNew computational tool may fuel vaccine development
La Jolla biologists harness machine learning and computational tools to make sense of immune system data.
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NewsNewly discovered mechanism behind cognitive decline in aging
US researchers say new mechanism could lead to new drugs and therapies to treat normal cognitive decline in aging.
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NewsAlcohol-associated liver disease linked to abnormal splicing deregulation
Splicing deregulation is potential drug target and diagnostic tool, but can be affected by alcohol consumption and thus chronic liver disease.
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NewsAre female mice better protected against obesity?
The University of California underwent a mouse study disclosing underlying sex differences in mice for obesity.
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NewsExtracellular vesicles could slow spread of fibrosis
US researchers studied the extracellular vesicles of fibrosis and find potential avenue for new treatments and therapeutics.