All Disease Research articles – Page 14
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NewsNew organoid emulates development of the human heart
The team are the first researchers in the world to successfully create an organoid containing both heart muscle cells and cells of the outer layer of the heart wall.
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VideoWebinar: The Role of Neuronal Metabolism in Early Drug Discovery
Learning about the mitochondrial role in a neurodegenerative disorder.
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ArticleThe role of ABCs in lupus: insights for developing precision therapies
Researchers from the University of Pittsburgh have found that age-associated B cells (ABCs) are key drivers of lupus, a chronic autoimmune disorder that attacks the patient's own organs.
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NewsNewly identified cell type could be key to preventing graft versus host disease
UW researchers at the Carbone Cancer Center have identified the cells that can cause graft versus host disease, the most common complication of bone marrow transplants.
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ArticleThe future of lab automation: streamlining drug research
In this article, Drug Target Review's Ria Kakkad and Izzy Wood explore the results of the latest research on lab automation techniques and technologies designed to accelerate drug discovery.
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NewsGround-breaking glycocalyx study could improve cancer immunotherapy
The researchers found that cancer cells with thicker glycocalyx barrier are better at evading immune cells.
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The immune system's power over antibiotics for infections
The natural process of removing damaged cell parts could present an alternative to antibiotics, especially where bacteria have become resistant to existing drugs.
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NewsNew genes modulate toxicity of the protein that causes Alzheimer’s
Scientists from Spain have identified genes that regulate Alzheimer’s disease, including Surf4, which alters the regulation of calcium within Alzheimer’s cells.
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WhitepaperApplication note: Single Cell Deposition Efficiency
Comparison of single cell dispensing efficiency between Namocell Single Cell Dispenser and limiting dilution method.
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NewsFirst molecular therapeutic for Angelman syndrome to advance into clinical trials
The scientists from Texas A&M have developed GTX-102, a novel therapeutic candidate to target Angelman syndrome by reactivating expression of deficient protein.
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NewsBiomarkers show promise for identifying early risk of pancreatic cancer
The finding is an critical first step towards classifying lesions on the pancreas that are at highest risk of becoming cancerous, enabling their removal before they start to spread.
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WebinarAccelerating hit finding programs: Echo MS and RapidFire-MS key advantages
In this on-demand webinar, we present the most advanced label-free technologies in identifying successful hit series for Hit-to-Lead and Lead-Optimization programs.
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NewsResearchers have created a new view of how B cells recognise threats such as viruses
The researchers say their new discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.
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NewsScientists discover therapeutic target that could treat glaucoma
The researchers found restoring mitochondrial homeostasis in the diseased neurons could protect the optic nerve cells from being damaged from glaucoma.
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WhitepaperGuide: Tips for Single Cell Isolation
Single cell isolation is a critical step for a number of workflows, and can greatly impact the success of downstream applications.
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Researchers find ancient virus genome drives autism
The scientists revealed in mice models that endogenous retrovirus activation increases a foetus’s susceptibility to autism.
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NewsTransporting antibodies across the blood–brain barrier to treat Alzheimer’s disease
Researchers have found a way to ensure that new Alzheimer’s medications are delivered to the right place in the body and at the right timepoint in disease progression, so that they have the best effect.
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NewsResearchers discover the role of intestinal fibrosis in inflammatory bowel disease
The scientists used a new in vitro platform, which allowed intestinal organoids to be cultured on an open lumen, planar system that could be manipulated experimentally.
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WhitepaperApplication note: Generating clonal GFP cell lines
Namocell single cell dispensers use gentle sorting pressure to isolate and dispense GFP-positive cells into 96-well plates.
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VideoWebinar: Accurate detection of mitochondrial toxicity
Using Agilent Seahorse XF technology with the XF Mito Tox Assay allows for streamlined, reliable identification of mitochondrial toxicants.