All articles by Drug Target Review – Page 56
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News
Research offers insight into swift spread of SARS-CoV-2 variants
Researchers have shown insights into the omicron variants of the SARS-CoV-2 virus, which have rapidly disseminated globally in the past year.
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NewsImmune cells predict flu symptoms
St. Jude Children’s Research Hospital, in collaboration with ESR Limited, discovered that specific immune cells present in individuals months before a flu infection can better predict symptom development compared to current antibody-based methods.
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NewsVaccine may reduce severity of long-haul covid symptoms
Receiving a COVID-19 vaccination could offer a dual benefit by not only lowering the likelihood of developing long-haul COVID but also mitigating symptoms for individuals already dealing with this condition.
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NewsImmunotherapy: antibody set for combating tumours
A recent study sheds light on the potential of artificial DNA structures that, when combined with antibodies, guide the immune system to target cancer cells specifically.
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News
Protein-triggered motor neuron loss in amyotrophic lateral sclerosis
The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the cerebral cortex to motor neurons in the spinal cord, which in turn activate muscles, enabling fluid motion. ...
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NewsDNA repair breakthroughs for innovative cancer treatment
This study explores cell survival, the continuous repair of DNA breaks is crucial. Failure to repair DNA effectively can result in mutations, contributing to the development of cancer.
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NewsModified neural stem cells for spinal cord injury
Using genetically modified human neural stem cells (hNSCs), researchers demonstrated that targeted manipulation of a specific gene expression within hNSCs can facilitate the restoration of damaged neural circuits and recovery of locomotor functions.
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News
Dynamic molecular aggregates within cells
Researchers from the University of Freiburg and the University of Cambridge have observed live cell formation of membraneless molecular aggregates, uncovering the interplay between biological mechanisms and physical force.
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CDK9 inhibitors for haematological malignancy treatment
A novel category of drugs, CDK9 inhibitors, emerges as potent agents capable of suppressing the transcription of these anti-apoptotic and pro-survival proteins.
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NewsArtificial intelligence cell analysis for swift blood disease diagnosis
Researchers from the German Cancer Research Center (DKFZ) and the Cambridge Stem Cell Institute have developed an artificial intelligence (AI) system capable of identifying and characterising white and red blood cells within microscopic images of blood samples. This AI algorithm holds the potential to aid medical professionals in diagnosing blood ...
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NewsNeuronal relocation facilitates healthy retina formation
During embryogenesis, organs must achieve a precise cell count and functional structure. Embryos efficiently manage multiple tasks—growth, shaping, and architecture establishment. Despite extensive research on embryonic development, the intricate coordination of these tasks in both space and time remains incompletely understood.
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NewsSickle cell anaemia: gene therapy insights for blood disorders
Cutting-edge research conducted by experts at Michigan Medicine, the Children’s Hospital of Philadelphia, and Penn Medicine is revolutionising the approach to treating blood disorders like sickle cell anaemia through innovative gene therapy methods.
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NewsResearchers discover covid-19 induces mitochondrial dysfunction
Since the onset of the COVID-19 pandemic caused by the SARS-CoV-2 virus, scientists have been striving to comprehend the underlying reasons for the virus's distinctive and detrimental long-term impacts, distinct from most other coronaviruses.
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NewsBreakthrough treatment defeats deadly fungus
Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a method to combat fungal infections by targeting their fatty acid production.
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ArticleEpisode 21 - Allogeneic cell therapies and the immune system
This episode defines allogeneic cell therapy as the administration of cells to a patient for therapeutic use, that were not initially taken from that patient.
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NewsBreakthrough in breast cancer detection
MIT has unveiled a wearable ultrasound device. Ingeniously designed to seamlessly integrate into a bra, this innovative technology opens new avenues for early breast cancer diagnosis.
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News
Unlocking the achilles' heel of insulin pump technology
Study led by UW Medicine reveals concerns about insulin pump therapy for type 1 diabetes patients. Long-term pump usage can lead to fibrotic, irritated infusion sites, making insulin delivery less effective
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NewsConversations about the NHS: a bold prescription for it’s future
As the NHS celebrates its 75th anniversary, healthcare leaders, policymakers, and practitioners have been sharing their innovative ideas on how to reshape and safeguard its future.
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NewsCadmium and foetal development
Researchers at Rutgers School of Public Health have made significant strides in comprehending the effects of cadmium, a toxic metal, on foetal development during pregnancy.
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ReportBeyond the lab: cell & gene therapy
The launch of our new series, "Beyond the Lab," promises to deliver high-level insights commissioned exclusively by Drug Target Review magazine. Our inaugural report is an exploration of the remarkable advancements in cell and gene therapy that are revolutionising the field of drug discovery.