All articles by Drug Target Review – Page 54
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NewsHuntington’s disease: a way to prevent cognitive decline
Discovery about Huntington’s disease may apply to other neurodegenerative disorders, like Alzheimer’s and frontotemporal dementia.
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NewsNew material engineered can repair severed nerves
Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.
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NewsProtective mutation found in kidney disease gene
A new discovery about a different protective genetic mutation in apolipoprotein L1 could have major implications for kidney health.
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NewsSCID-X1 gene therapy successful with 3D genome architecture
New research improves patient care by finding where gene copies integrate into DNA and using lentiviral vectors.
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NewsHuman-derived proteins used in DREAM tool
CRISPR-DREAM tool used to activate insufficiently expressed genes and convert skin cells to induced pluripotent stem cells (iPSCs).
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NewsMidbody remnants following mitosis could combat cancer
Midbody’s role in cell signalling and stimulating cell proliferation offers an opportunity to detect cancer.
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NewsPancreatic tumours fooled by glutamine mimic
A novel treatment approach using DON molecule starves tumours of essential nutrient, significantly slowing tumour growth.
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NewsAI: age prediction model on human brain tissue developed
For the first time ever, researchers have developed an algorithm to predict age at death and indicate early changes related to disease.
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NewsIncreased pain sensitivity in Neanderthal gene variants
Three gene variants in SCN9A gene, implicated in sensory neurons and inherited from Neanderthals, result in increased pain sensitivity.
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ArticleeBook: Advancing 3D Culture Imaging For Biopharma
Download this FREE eBook, which explores some of the challenges encountered when imaging 3D culture models such as organoids and spheroids, and sheds light on innovative microscopy solutions that can empower scientists to make new advances in areas such as regenerative medicine, drug discovery, and disease research.
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ArticleEpisode 23 - Making organoids ready for screening
Tune into this podcast to understand why researchers are turning to 3D Organoids and how organoids can be made ready for screening.
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Neutrophils: vital defence against fungal toxin
New research uncovers how neutrophils trigger cellular processes to counteract the Candida albicans toxin.
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NewsGene expression signatures improve prognostic ability
Thousands of breast cancer gene expression signatures analysed.
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Spectra: new insights to improve immunotherapy treatments
New open-source computational method called Spectra improves analysis of single-cell transcriptomic data.
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NewsNutrient programmes immune cells to battle infection and cancer
Research suggests immune and non-immune cells can be reprogrammed by changing how nutrients are used.
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Vascular cells essential in forming long-term memories
New research reveals capillary cells and neurons work together to ensure memory formation and storage.
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Genetic scar left in the genome of bacteria
New study reveals how pneumonia cells become resistant to penicillin through evolutionary gateway.
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NewsChildhood cancer survivors’ mortality risk
Researchers find genetic explanation for increased risk of developing second cancers.
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Explosive cell death: inflammation-causing gene
WEHI researchers have found that a genetic change of MLKL increases risk of uncontrolled inflammatory response
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ArticleDrug Target Review Neuroscience eBook 2023
Explore cutting-edge neuroscience insights through an exclusive interview with Dr Olga Chechneva on nuclear interactions in the mouse brain and a groundbreaking study by MIT researchers revealing key aspects of Alzheimer's disease. Download your FREE eBook!