All articles by Izzy Wood (Drug Target Review) – Page 9
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NewsDiscovery of novel mechanism for MRSA virulence
US researchers revealed that MRSA has undergone repeated mutations in the sarZ gene, leading to increased severity of blood stream infections in mouse models.
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NewsUnexpected neuronal molecule makes prostate cancer more aggressive
US researchers discover a potential therapeutic avenue through the molecule NgR2, against an aggressive form of prostate cancer.
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NewsNew treatment for MS using artificial nerve fibres
Danish researchers undertake a new project that aims to find new forms of treatment for diseases such as MS, which breaks down myelin and nerve fibres, by developing new, artificial nerve fibres
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ArticleTransformational vaccines that address global health challenges
Drug Target Review’s Izzy Wood spoke to Joseph Hernandez, CEO of Blue Water Vaccines, about developing transformational vaccines to address significant health challenges globally.
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NewsNew system for safer CRISPR-based gene drive testing and development
US researchers outline the development of a new system for testing and developing CRISPR-based gene drives in the laboratory, and safely converting them into tools for potential real-world applications.
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NewsSARS-CoV-2 antibodies can bind to two viral targets at once
US researchers find that SARS-CoV-2 bivalent antibodies can continue to neutralise Omicron and Omicron lineages.
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NewsNovel therapeutic approach aims to prevent ARDS
UCLA researchers have found peptide blocks that cause the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.
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NewsMajor lung cancer mechanism can be used to evade immune attack
US researchers found high levels of XBP1s in lung cancer cells, which plays a key part in regulating the local immune environment in lung tumours, and can be disabled to increase anti-cancer immunity
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NewsNew database maps proteins that could predict cancer
Swedish researchers unveiled a new cancer protein profile database compiled from artificial intelligence and machine learning.
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NewsA change in genetic code causes lung cancer to develop
Using lung basal cell organoids, researchers identify a gene that directs the development of lung cancer and offers a better understanding of its disease treatment.
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NewsMathematical model predicts long-term effectiveness of COVID-19 vaccine
US scientists have designed a mathematical model that can predict COVID-19 vaccines’ effectiveness over the long term in healthy individuals and those who have cancer or suppressed immune responses.
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NewsNew insights on the structural biology of medical cannabis
French researchers underwent a structural study showing that THC cannabinoids inhibit a human enzyme called autotaxin.
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ArticleCould drinking green tea, red wine and beer prevent Alzheimer’s?
In this article, Drug Target Review’s Izzy Wood reviews some of the latest Alzheimer's disease research, highlighting the progress that has been made toward new, more unique therapeutic strategies against Alzheimer’s.
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NewsHumanised mouse model identifies the best match for organ donor
US researchers have developed a mouse model that holds promise in identifying the best organ donor and showing early signs of transplant rejection.
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NewsMemory loss could be solved using an asthma drug
Dutch researchers, using optogenetic approaches and an asthma drug, discovered that memory loss from sleep deprivation can be retrieved.
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NewsNovel protein coordinates melanin production
Japanese researchers reported that a key transcription factor “Nrf3” regulates the process of melanin production in mouse and human cells.
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NewsCell organisation determined by new mathematical framework
US scientists, using high-resolution imaging, debuted a new way to see cell organisation and rich variation in cell shape
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NewsStem cell model shows early stages of differences in sex development in mice and humans
Israeli researchers develop new model that will help pinpoint complications in individuals with Differences in sex development (DSD).
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NewsSynthetic tissue helps restore and repair erectile function in animal models
Chinese scientists have developed a synthetic tissue that repairs penile injuries and restores normal erectile function in pigs.
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News50 year old blood pressure drug offers alternative treatment for PTSD
US scientists offer a new purpose for the blood pressure drug clonidine as a treatment to reduce the affects of PTSD.