All articles by Izzy Wood (Drug Target Review) – Page 4
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ArticleRNA processing in health and disease: challenges and opportunities of the field
In this interview, Sam Hasson, Senior Director at Rgenta Therapeutics, shares his journey in drug discovery, from graduate school to industry, and his current work developing small molecule therapeutics to target RNA processing. He discusses the challenges and opportunities in the field of RNA-centric drug discovery and highlights the potential ...
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NewsPredicting cerebrovascular diseases with retinal imaging
New imaging approach reveals that changes in retinal microcirculation may indicate cerebrovascular diseases that involve reduced blood flow.
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News$6 Million grant issued to Penn Medicine to investigate role of DNA in cardiac cell development
Penn Medicine researchers are interested in how cardiac cells use DNA to establish and maintain their specification.
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NewsViruses can cause brain cells to fuse leading to a malfunctioning CNS
Researchers from Australia explore how viruses can alter brain cells, and thus the functions of our nervous system, leading to neurological symptoms.
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NewsNew method of designing drugs without side effects
Japanese researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects.
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NewsPrecision oncology aids prospects for biliary tract cancer
A study out of Austria suggests gene changes in those with biliary tract cancer offers new avenues for new precision oncology therapies.
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Ancient virus holds connections to ALS in people
US study identifies promising new target, in protein remnants from an ancient virus, for treating underlying cause of ALS.
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NewsNew treatment options for chronic kidney disease
Fresh insights from University of Edinburgh into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease.
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NewsNerve regeneration offers hope for blindness and paralysis
US researchers uncover that certain nerve cells that have the capacity to regrow, are necessary for axon regeneration, providing hope for conditions like blindness and paralysis.
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NewsGenomic sequencing helps find treatment for rare genetic skin disorder
US researchers use genome sequencing to reveal genetic basis for disabling pansclerotic morphea, a severe inflammatory disease.
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NewsNeurons that are responsible for recognition
Researchers from South Korea uncover that neurons in the hippocampus play a crucial role in assigning positive value through interactions with others.
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NewsNovel mutation linked to late-onset Alzheimer's disease
Chinese researchers discover a mutation, referred to as the "Shanghai APP" mutation, which has been linked to late-onset Alzheimer's disease and offers fresh insights into the disease's underlying molecular mechanisms.
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NewsScientists create first humanised mouse model for rare genetic disease
German researchers have successfully developed mice with a defected human gene responsible for congenital adrenal hyperplasia (CAH), a rare genetic disease.
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NewsAmino Acid PET effective in distinguishing brain metastases from treatment-related changes
US study uncovers the best way to treat recurrent or progressive brain metastases using an amino acid PET technique.
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NewsNew algorithm can predict diabetic kidney disease
Researchers from US and Hong Kong have found that a simple blood sample may help doctors catch kidney disease earlier in type 2 diabetes patients
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NewsNovel approach stimulates DNA repair mechanisms to combat a leading cause of autism spectrum disorders
US researchers report promising results for fragile X syndrome, by stimulating cells' DNA repair mechanisms that could correct the inherited genetic defect associated with the disorder.
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NewsMolecular biology behind memory development in early childhood
Researchers from Canada develop a greater understanding about the molecular mechanisms for memory development in early childhood.
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NewsNew study uncovers DNA repair mechanism in bacterial cells
US research reveals mechanism used by bacterial cells to repair their faulty DNA, which could help scientists understand the intricacies of DNA repair processes.
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NewsDiagnosing inflammatory diseases with synthetic peptides
Researchers from Switzerland identify peptides that detect and measure a key biomarker in inflammatory conditions.
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NewsExamining brain’s glymphatic system may shed light on brain diseases
US researchers used focused ultrasound with microbubbles to examine glymphatic system of the brain, which plays a crucial role in clearing metabolic waste from the brain.