All articles by Izzy Wood (Drug Target Review) – Page 5
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NewsLinking air pollution and lung disease
USC researchers gain valuable insights into the biological processes underlying the association between air pollution and lung disease. By unravelling the mechanisms involved, researchers are hopeful that new strategies can be developed to mitigate the adverse effects of pollution exposure and improve the prevention and treatment of related diseases.
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NewsTargeted therapy for treatment-resistant breast cancer
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.
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News3D models used to investigate bacteria motility
US researchers created a 3D model of the bacteria: Helicobacter pylori, to better understand its motility, in order to develop new treatments for bacterial infections.
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NewsPotential pathway to improved stroke recovery
Japanese researchers identify a protein that reduces inflammation, stimulates neural growth, and improves sensory and motor functions following ischemic stroke in mice.
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NewsDiverse senescent cell populations uncovered by single-cell RNA sequencing
Single-cell transcriptomic RNA sequencing analysis has allowed US researchers to identify the specific populations and the dynamic transition states during senescence initiation and progression.
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NewsNew technique enables in vivo analysis of protein complexes
Chinese researchers use a glycosidic-bond-based mass-spectrometry-cleavable cross-linker to analyse proteins in vivo.
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NewsAre tiny brain organoids legally a person?
Japanese researchers debate if human brain organoids that are cultivated from stem cells and serve as a model of human brain development, can be legally considered a person.
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NewsCancer-killing benefits of popular obesity treatment
Findings from the Republic of Ireland, in relation to GLP-1 obesity treatment showcase its ability to restore the body’s natural cancer-killing defences.
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NewsAntibiotic-resistant bacteria contaminates hospitals’ ICU in China
The drug resistant bacteria: CRAB, came into the ICU in hospitals in Hangzhou, China, creating an urgent need for a thorough understanding of the persistence, transmission, and evolution of CRAB populations in such environments.
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NewsCustomising T cell-based immunotherapies to treat cancers
US researchers usings a ‘SNAP’ receptor system can customise immunotherapies for targeted treatments of cancer and other diseases.
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NewsComputational tool gets more out of multi-omics data
US researchers developed a next-generation computational tool called NetBID2 that can uncover difficult-to-identify proteins that drive biological processes contributing to cancer.
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NewsSpecial omega-3 fatty acid lipid plays critical role in the ageing brain
Scientists from Singapore have sought to understand the role of Mfsd2a in brain cells, in transporting lysophosphatidylcholine (LPC), a lipid that contains an omega-3 fatty acid
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Helper T cells may hold key to precision allergy treatment
US researchers have connected a rare T cell called Th9 with treating allergies, testing in mouse models with asthma.
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NewsReviving T cells to tackle immunotherapy-resistant cancers
US researchers utilise a new approach to immunotherapy, using exhausted T cells that could help overcome treatment resistance in cancers.
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NewsChances of eliminating HIV infection increased by dual gene-editing method
US researchers suggest that combing a dual gene-editing approach with antiretroviral drugs can eliminate HIV infections in animal models.
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NewsScientists uncover new insights into rare childhood liver cancer
Researchers from the Netherlands have utilised organoids and the CRISPR-Cas9 "molecular scissor" system to better understand the features and biology of fibrolamellar carcinoma (FLC), a rare type of liver cancer that affects adolescents and young adults.
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NewsBlocking a microRNA may prevent age-related conditions
Conditions like chronic inflammation, muscle loss and bone loss have an elevated microRNA, US researchers attempted to block this in aged mice.
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NewsResearchers establish the first human respiratory organoid culture system
A team from the University of Hong Kong has developed the first human respiratory organoid culture system, using it to unveil a novel mechanism for the high transmissibility of the SARS-CoV-2 Omicron variant.
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NewsStudy links nutrients, brain structure, cognition in healthy aging
US researchers found that nutrient intake, brain structure and cognitive function contribute to healthier brains in aging adults, by looking at correlating blood markers.
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NewsGenetics behind facial and skull changes in Down Syndrome mouse model
Progress in identifying the gene responsible for facial and skull changes in mouse model of Down Syndrome, made by UK researchers.