All Rare & Genetic Disorders articles – Page 7
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NewsNewly discovered mechanism behind cognitive decline in aging
US researchers say new mechanism could lead to new drugs and therapies to treat normal cognitive decline in aging.
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ArticleGenetic variant identification: unveiling the power of STING-seq
In an exclusive interview, Dr Neville Sanjana, Associate Professor of biology at NYU and a core faculty member at the New York Genome Center, discusses the breakthrough study on STING-seq.
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NewsSubstance abuse inhibits cognitive flexibility
New US research underlines the relationship between substance use and significant modifications to an inhibitory brain circuit, resulting in decreased cognitive flexibility
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NewsNew biomarker identified for major depressive disorder
Local gyrification index, which measures cortical folding in the brain, could be a novel neuroimaging marker for major depressive disorder.
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ArticleAdvancing gene editing to redefine therapies across genetic disease
In the unmet need for effective treatments to alleviate suffering and prevent premature death across the spectrum of genetic diseases, Brent Warner, Poseida Therapeutics, shares that the ability to edit DNA holds hope for patients currently experiencing incurable genetic diseases and has spurred ongoing efforts to develop and improve gene ...
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NewsPlacenta's role in genetic risk of schizophrenia
A recent study led by the Lieber Institute for Brain Development has revealed that over 100 genes associated with the risk of schizophrenia appear to contribute to the development of the illness primarily through their influence on the placenta.
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NewsLinking air pollution and lung disease
USC researchers gain valuable insights into the biological processes underlying the association between air pollution and lung disease. By unravelling the mechanisms involved, researchers are hopeful that new strategies can be developed to mitigate the adverse effects of pollution exposure and improve the prevention and treatment of related diseases.
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NewsAntibiotic-resistant bacteria contaminates hospitals’ ICU in China
The drug resistant bacteria: CRAB, came into the ICU in hospitals in Hangzhou, China, creating an urgent need for a thorough understanding of the persistence, transmission, and evolution of CRAB populations in such environments.
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ArticleCRISPR and single-cell sequencing highlight genetic variants for traits and diseases
This article highlights a new approach to address human genetics, using STING-seq which provides roadmap to identify variants and genes, enabling deeper understanding of the noncoding genome and targets for therapies
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ArticleRevolutionary nanoparticles enable gene-editing in lungs
This article outlines the development of a new type of nanoparticle that can perform gene-editing in the lungs. Scientists from MIT and the University of Massachusetts Medical School have collaborated to create this Ribonucleic acid (RNA) delivery particles, which have the potential to revolutionise the treatment of lung diseases such ...
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NewsImproved cognitive function in rats with serine racemase upregulation
US researchers have found that increasing the expression of the enzyme serine racemase in the prefrontal cortex of middle-aged rats can enhance cognitive function.
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NewsStudy identifies microbe-gut signalling as potential new treatment for IBD
New research from Cincinnati Children’s Hospital Medical Center suggests blocking IL-22 and IL-1R could offer a promising IBD treatment.
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NewsNew self-powered drug delivery system
US researchers have invented a drug delivery technology that has implications for opioid epidemic, cancer treatment, rehabilitation care and more.
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NewsScientists create organoid to understand hearing loss
The ground-breaking study is an important step towards modelling cochlear function in a dish.
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NewsExperimental antidepressant could also treat alcohol use disorder
A US pre-clinical study investigating the antidepressant: MAP4343, discovered it reduced alcohol intake in a mouse model of alcoholism.
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NewsDifferent cardiac reactions to stress hormone in mouse study
US researchers use new imaging technique to see cardiac reactions to noradrenaline, the ‘fight or flight’ hormone.
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NewsNovel therapeutic approach aims to prevent ARDS
UCLA researchers have found peptide blocks that cause the damaging lung inflammation seen in acute respiratory distress syndrome, or ARDS.
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News50 year old blood pressure drug offers alternative treatment for PTSD
US scientists offer a new purpose for the blood pressure drug clonidine as a treatment to reduce the affects of PTSD.