All Cancer articles – Page 26
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NewsControlling MYC’s hyperactivity with a peptide compound
A novel peptide can suppress MYC by binding directly to it with sub-micro-molar affinity, advancing cancer drug development.
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ArticleAllosteric control sites in KRAS protein found
The first complete control map for any protein has been made for KRAS, and four potential drug targets have been discovered.
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NewsTargets for pancreatic cancer treatment found
Using tumour organoids, researchers have found a starting point for the development of a more refined PDAC drug.
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ArticleNot all neoantigens are created equal
Founder and CSO of Achilles Therapeutics Dr Sergio Quezada reveals how the landmark TRACERx study has gleaned key insights that could make the difference between success and failure in immunotherapy treatment.
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ArticleThe potential of CD24 in cancer immunotherapy
Cofounder & Chief Scientific Officer of Pheast Therapeutics, Dr Roy Maute, reveals his company’s promising drug candidate and explains why they have focused on their chosen target.
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NewsHow gene regulatory networks maintain FLT3-ITD mutated AML
Using shRNA screening enabled researchers to investigate the roles of individual specific factors in maintaining the network found in AML.
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NewsNew insights about the development of hematopoietic stem cells
Understanding the involvement of Nod1 in the development of blood stem cells could greatly improve blood disorder treatments.
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ArticleDrug Target Review - Issue 4 2023
A new Drug Target Review issue is now ready to download! This issue features articles on CRISPR, personalised medicine and screening.
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NewsThe influence of the immune system on early human lung growth
Understanding the mechanisms in lung formation could develop new therapeutic approaches for respiratory conditions.
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ArticleNew understanding of the TMEJ pathway in cancer
Cancer treatment may be majorly impacted by new findings about the polymerase theta-mediated end joining time DNA repair pathway.
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News
Perivascular fibroblasts support glioblastoma tumours
Glioblastomas can resist immunotherapy as perivascular fibroblasts support the creation of an immunosuppressive tumour environment.
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NewsNew organoid model of neuroendocrine tumours developed
NETs require epidermal growth factor to grow, meaning that inhibiting EGF receptors could treat these types of tumours.
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WhitepapereBook: A Microscopy Guide For Spatial Biology
In this eBook, discover how to better understand tissue landscapes with different microscopy techniques including multiplex imaging.
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NewsGene therapy reduces hepatocellular carcinoma in mice
Increasing microRNA-22 overexpression in a gene therapy approach treated HCC in mice, offering promise for its prevention and treatment.
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NewsAn altered protein can combat the growth of leukaemia cells
Discovery about the NPM1c variant could lead to new drugs targeting the cell growth of acute myeloid leukaemia.
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ReportBeyond the lab: cancer research
Our inaugural report is an exploration of the remarkable advancements in cancer research and the field of drug discovery.
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NewsTumour metastasis is blocked by nanodiamonds
Carboxylic nanodiamonds could be a therapeutic agent for cancer, as melanoma cells treated with them showed little to no metastasis.
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Understanding the genetic origins of disease variation
Researchers, using high-resolution mapping and mathematical modelling, have found mechanisms controlling mutation-driven diseases.
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Discovery of molecular pathway could target lung cancer
New findings about how RBM10 inhibits lung cancer growth offers potential for an anti-cancer drug and more personalised treatment.
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NewsPancreatic cancer initiates an immune system response
Studying pancreatic ductal adenocarcinoma tumours, researchers discovered 25 antibodies that responded to antigens.