All Neurological disorders articles – Page 5
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NewsPlatelet-inspired nanoparticles could improve treatment of inflammatory diseases
Scientists have developed platelet-inspired nanoparticles that deliver anti-inflammatory drugs directly to brain-computer interface implants, doubling their effectiveness.
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ArticleProtein folding interference: a new path to hard-to-drug targets
Protein folding interference offers access to targets long considered unreachable by traditional drug discovery. By acting on transient folding intermediates, this approach presents a new opportunity to eliminate disease-driving proteins.
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NewsNew reverse genetic system accelerates norovirus vaccine research
Researchers at The University of Osaka have developed a new system to study human norovirus, with the hope of being able to develop vaccines and antiviral treatments faster.
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NewsNew beta lab platform to streamline early-stage research
UK life science software company Lab Thread has launched the beta of its unified lab platform, designed to streamline research workflows.
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NewsLive-cell liquid biopsy study aims to transform cancer treatment
Vortex Liquid Biopsy Solutions has launched a new clinical study with The Doctors Laboratory to assess how its live-cell liquid biopsy technology could change cancer monitoring and treatment.
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NewsLife sciences face ‘scientific content crisis’ in AI adoption
A new survey by the Pistoia Alliance reveals a growing ‘scientific content crisis’ in life sciences, showing that incomplete data and weak governance are limiting the accuracy and adoption of AI in research and development.
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NewsTY1: new experimental drug restores tissue after heart attack
Scientists have developed an experimental RNA-based drug, TY1, that repairs DNA, reduces scar tissue and could lead to new treatments for heart attacks and autoimmune diseases.
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ArticleThe partnership changing the pace of radiopharmaceutical development
A new collaboration between Crown Bioscience and Medicines Discovery Catapult is bringing advanced tumour models together with world-class imaging and radiochemistry to accelerate the development of next-generation radiopharmaceuticals.
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NewsResearchers identify new drug site on epilepsy target SV2A
A team led by St. Jude Children’s Research Hospital and UT Southwestern has mapped how key anti-epilepsy drugs latch onto their neural target, SV2A.
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NewsRomidepsin drug combo proves effective against resistant childhood cancer
Australian researchers have identified a promising drug combination that can bypass treatment resistance in relapsed neuroblastoma, offering hope in the fight against one of the deadliest childhood cancers.
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ArticleMapping the genome in 3D to reveal new drug targets
Find out how a three-dimensional view of the genome is giving scientists a clearer picture of disease biology and revealing new opportunities for targeted therapies.
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NewsOTULIN enzyme found to control tau production in Alzheimer’s
New research has shown that the enzyme OTULIN regulates tau at the gene-expression level rather than through protein degradation.
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NewsOral arginine reduces harmful amyloid in Alzheimer’s models
A naturally occurring amino acid commonly found in supplements has reduced harmful amyloid build-up and eased symptoms in animal models of Alzheimer’s disease.
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ArticleAdvancing disease biomarker research with EV multiplex profiling
Vanitha Margan, Global Product Manager for Bio-Plex Multiplex Immunoassays at Bio-Rad Laboratories, reveals how multiplexing is being used to realise the full potential of extracellular vesicles in disease monitoring.
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NewsNew CAR-T cell therapy capable of destroying glioblastoma cells
A new CAR-T treatment developed in Switzerland has shown striking early success against glioblastoma, one of the deadliest brain cancers, and is now moving towards human trials.
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NewsBacterial traces discovered within gliomas and brain metastases
Scientists have discovered active bacterial traces inside brain tumours, overturning assumptions about the brain’s sterility and opening up new possibilities for understanding – and potentially treating – gliomas and brain metastases.
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NewsScripta Therapeutics raises $12m to advance neurodegenerative research
Oxford-based techbio start-up Scripta Therapeutics has announced a $12 million seed funding round helping them to reshape conventional drug discovery.
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ArticleCircular RNA technology: the future of gene therapy
Pioneering circular RNA could redefine what the future of gene therapy looks like. Erik Digman Wiklund, CEO of Circio, shares how his company’s platform is enhancing gene expression and tackling toxicity challenges through smarter design and scientific collaboration.
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NewsHow a psychedelic found in mushrooms could help fight alcoholism
Scientists have discovered that psilocin – the compound produced in the body from the psychedelic found in magic mushrooms – may reduce alcohol consumption by calming activity in brain regions linked to stress.
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ArticleNasal drug delivery: the non-invasive future of treatment
Advances in formulation science and device technology are transforming nasal drug delivery, enhancing absorption, stability and patient adherence. This article examines the innovations driving its growth and highlights future applications ranging from systemic treatments to nose-to-brain therapies and vaccines.