SARS-CoV-2 spike protein dihedral angle oscillations reveal favoured rotation frequencies
As new variants of the SARS-CoV-2 virus emerge, leading scientists Dr Oscar Bastidas and Dr Zoran Sevarac explore how their latest research identified a structured frequency domain profile in data with no discernible pattern. Their article also emphasises that it remains imperative to continue learning about this pathogen’s molecular machinery ...
COVID-19 continues to be a worldwide health hazard and pandemic. With new variants continuing to surface and spread, characterising viral proteins that are crucial to the infection process continues to be a pressing research topic.
Our research efforts seek to characterise, more thoroughly, the SARS‑CoV-2 spike (S) protein, which is a key player in the infection process of host epithelial cells.
In our recent study, we assessed molecular dynamics data chronicling the time-dependent behaviour of phi and psi dihedral angles for each residue in each chain of the S protein, to see if there were any defining characteristics....
