COPD drug roflumilast may help fight breast cancer lung metastasis

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University of Colorado Anschutz Cancer Center scientists have uncovered how metastatic breast cancer cells exploit pulmonary repair pathways to establish tumours in the lungs. 

Breast cancer is often treatable in its early stages, but once it spreads to the lungs, options become limited. Now, researchers have discovered how tumour cells hijack the lung’s natural repair system to fuel their own growth — and found that an existing drug could slow the process.

This breakthrough could lead to new ways of treating metastatic breast cancer, targeting not just the cancer cells themselves but the environment that allows them to thrive.

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