Advancements in hit identification for membrane protein drug discovery

2025-04-07T09:00:00

G-protein-coupled,Receptors,(gpcrs),From,Left,To,Right,,Rhodopsin,,T-cell,Receptor

GPCRs are crucial drug targets, but their complex structures present significant challenges in drug discovery. In this article, Domainex’s Philip Rawlins explores how fragment-based screening and innovative technologies like PoLiPa are helping to overcome these hurdles, with a focus on the Adenosine A2a receptor.

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