CD47 protein found to drive glioblastoma growth
University of Adelaide researchers have discovered that CD47, a protein known for helping cancer cells evade immune detection, also directly promotes glioblastoma growth and invasion through a novel molecular pathway involving ROBO2 stabilisation.
Glioblastoma is one of the most aggressive and elusive brain cancers, with even the most advanced treatments failing to fight it effectively. Now, a new discovery by Australian researchers has found a hidden role played by a protein scientists thought they already understood.
This unexpected finding gives scientists an entirely new way of targeting the tumour at a molecular level. If confirmed, it could mark a turning point in the fight against glioblastoma, offering hope for therapies that are more precise, more effective, and potentially life-extending.
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