Whitepaper: Correlate protein expression with genomic data and IHC

Measure protein, DNA and RNA in FFPE tissue samples using rigorously IHC validated CST antibodies on the NanoString® nCounter® platform.

In this app note, we demonstrate multi-analyte characterization of non-small cell lung cancer (NSCLC) FFPE samples. IHC-validated, NanoString Barcoded antibodies were used to compare abundance of key signalling proteins, in parallel with analysis of RNA transcript abundance and DNA single nucleotide variant (SNV) mutations on the NanoString® 3D Biology™ and nCounter® platform. We present results demonstrating concordance of RNA/protein quantification with clinical gold standard IHC methodology.