Learn how Simple Western automated immunoassays screen degraders and IMiD compounds to quantify degradation activity, providing accurate DC50 and Dmax values.
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Identifying allosteric modulators and biased agonists for clinically relevant GPCRS. Case Studies using Eurofins Discovery’s GPCR product solutions.
Application note: Evaluation of different ion-pairing reagents for LC/UV and LC/MS analysis of oligonucleotides
The effect of various ion pairing reagents (amines and acidic counterions) on the LC/UV and LC/MS analysis of oligonucleotides (ONs) has been studied.
This tissue-specific handbook brings you key publications, in-house protocols and troubleshooting recommendations for your organoid cell culture.
Remdesivir is being prescribed under FDA emergency use authorization as a treatment for patients with COVID-19.
Discover how workflows are being accelerated to speed up the vaccine research and development process while maintaining safety and immunogenicity.
Getting a drug product to market can be a challenging process with lots to consider, but Recipharm’s team of experts is here to support you.
Application note: Accurate measurements on the Octet platform without added sample purification steps
Bioanalytical systems have rapidly developed over the past 10 years for lead selection during cell-line development. The advanced technologies for the timely and cost-effective screening of antibodies or vaccines involve consideration of quantitation, kinetics and other critical quality attributes (CQA).
Having the ability to get the maximum amount of data out of every slide is of crucial importance in a range of microscopy applications. Achieving this requires maximising the usable area on the slide, the number of observation modes and the number of fluorescent labels available, as well as optimising…
Quantitative reverse transcription PCR (RT-qPCR) involves the detection and quantification of RNA.
The Vi-CELL BLU automates the widely accepted trypan blue dye exclusion method for cell viability that has historically been performed with a light microscope, pipette, and a hemacytometer.
Identify therapeutic effects and adverse responses to compounds earlier in the drug discovery process.
A major challenge within electrophysiology labs is 50 or 60 Hz line frequency electrical noise, which can either distort or completely drown out biological signal.
Combining 2D and 3D models with live-cell assays allows monitoring of cell responses in real time and provides important insights about compound treatment effects, biological complexity, and physiological relevance of assay results.
Learn how to perform complex analysis of calcium oscillations and assess cellular and mitochondrial toxicity.