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Application note: Increasing throughput with dual emission AlphaLISA-AlphaPlex assay and simultaneous dual emission detection

5 October 2018 | By

Multiplexing AlphaLISA type assays will increase throughput while sample expenditure and costs are minimized. The ability of the PHERAstar FS microplate reader to perform simultaneous dual emission detection of this assay will allow users to double the information obtained from each well in the same amount of time as needed…

Application note: NanoBRETTM assay for monitoring of ligand binding to GPCRs in live cells, using the CLARIOstar® and the PHERAstar® FS

17 September 2018 | By

Due to the crucial role of G protein-coupled receptors (GPCRs) in mediating cellular responses to external stimuli, these receptors have been and will remain a prime focus for medical research and the pharmaceutical industry for many years to come. Their importance is especially highlighted by the statistic that 30-50% of…

Application Note: Evaluating the specificity and potency of PD-1 and PD-L1 blocking antibodies using AlphaLISA human and mouse PD-1/PD-L1 binding kits

5 September 2018 | By , , ,

Cancer immunotherapy utilises components of the immune system to treat cancer patients. These therapies are designed to work with a patient’s immune system to increase native anti-tumour responses. One type of immunotherapy relies on antibodies to bind to and inhibit the function of proteins expressed by the cancer cell...