Application note: Tools and protocols for high-content imaging and analysis
14 May 2019 | By Thermo Fisher Scientific
Integrating hardware, software, and fluorescent labels for optimised HCA assay development.
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Whitepapers
Application note: Laser technology for high-content imaging and analysis
14 May 2019 | By Thermo Fisher Scientific
Introducing the CellInsight CX7 LZR High-Content Analysis Platform - an updated version of our CellInsight CX7 instrument with advanced laser technology.
Application note: Tools for 2D and 3D neuronal cell culture
14 May 2019 | By Thermo Fisher Scientific
From the B-27 Plus Neuronal Culture System to fluorescent probes for cell analysis. Publication history of B-27 supplements demonstrates that researchers are expanding its use, far beyond the long-term culture of rat hippocampal and cortical neurons.
Application note: Fuelling discovery with high-content imaging and analysis
10 May 2019 | By Thermo Fisher Scientific
HCA platforms automate image capture and data analysis, giving researchers the sample sizes and precise quantitation tools required for research.
Whitepaper: TruBIOME™ increases mouse model reproducibility
1 May 2019 | By Taconic Biosciences
Ensure reproducibility with TruBIOME™ - the unique approach to generating research model colonies, which allows you complete control over their microbiome, from conception to cohort delivery.
HCA: Phenotypic fingerprint of cellular function
25 April 2019 | By ThermoFisher Scientific
High-content analysis app note: Phenotypic fingerprint of cellular function following gene editing by high-throughput imaging acquisition and analysis.
HCA Application note: New way of measuring synaptic function
25 April 2019 | By ThermoFisher Scientific
High-content analysis: monitoring neurite morphology and synapse formation in primary neurons for neurotoxicity assessments and drug screening.
Application note: Fast track antibody discovery
7 March 2019 | By Sphere Fluidics Ltd.
Learn more about an emerging high-throughput method for identifying and isolating rare cells secreting antigen-specific antibodies.
Whitepaper: The most important mouse in the world: the utility and applications of C57BL/6 models
10 January 2019 | By Taconic Biosciences
Learn everything you need to know about the most widely-used mouse in biomedical research with this free whitepaper.
Whitepaper: Application of CRISPR/Cas to the generation of genetically engineered mice
7 January 2019 | By Taconic Biosciences
Learn how the continued development of CRISPR gene editing technologies opens fresh possibilities for in vivo model design.
Application note: Rapidly isolate high-producing clones
21 December 2018 | By Sphere Fluidics Ltd.
Find out how to streamline Cell Line Development by identifying high-producing clones with monoclonality assurance in one day.
Application note: GABAA Receptors
11 December 2018 | By SB Drug Discovery
SB Drug Discovery shows the validation of fluorescence and automated electrophysiology assays designed to assess agonists, antagonists and allosteric modulators of these receptors, culminating in a high-throughput electrophysiology assay suited to assessing multiple GABAA receptor subtypes on a single assay plate.
Application note: Production of human induced pluripotent stem cell-derived cortical neurospheres in the DASbox® Mini Bioreactor System
29 November 2018 | By Eppendorf
There is substantial interest in the scientific community in using human induced pluripotent stem cell (hiPSC)-derived neural cells to study basic mechanisms of brain development, neuronal function, and drug-induced effects. In vitro-generated brain organoids are promising models, because they show a remarkable degree of maturation and can be kept in…
Application note: Sensitive fluorometric quantification of DNA in microplate format
29 November 2018 | By Thermo Fisher Scientfic
This technical note demonstrates the feasibility of using the Thermo Scientific™Fluoroskan™ or Fluoroskan FL instruments with the Invitrogen™ Quant-iT™ dsDNAhigh-sensitivity assays. Sensitive and specific quantification of double-stranded DNA is carried out in microplate format. This is part of a series of technical notes aiming to help customers choose the best…
Application note: Enabling single-software multiple attribute methodology (MAM) for the assessment of biopharmaceutical product quality attributes
29 November 2018 | By Fan Zhang, Sean McCarthy, Zoe Zhang
Development and production of biopharmaceuticals is complex. Even minor impurities, or changes in attributes such as glycosylation or charge heterogeneity, can have a profound impact on the safety and efficacy of the final product. Traditionally, multiple analytical techniques have been required to assess the full range of biopharmaceutical product attributes.…
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