Whitepaper: Smart cell monitoring
3 May 2018 | By Del Trezise, Essen BioScience
This whitepaper outlines how advances in real-time live-cell monitoring and analysis methods are addressing these changing needs.
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Whitepapers
Application note: CRISPR/Cas9 genome-edited cells express nanoBRET-donor that monitors protein interaction and trafficking
12 April 2018 | By BMG Labtech GmbH, Carl White (Molecular Endocrinology and Pharmacology), Ethan See (The University of Western Australia), Kevin Pfleger (Dimerix Limited)
In this application note, BMG Labtech discuss how the Bioluminescence resonance energy transfer (BRET) is a versatile tool to study interactions and trafficking in proteins.
Application note: Simultaneous dual phosphoprotein target analysis with Alpha Terbium SureFire Ultra Multiplex
20 March 2018 | By Andrea Brown (TGR BioSciences), Antony Sheehan (TGR BioSciences), Michael Crouch (TGR BioSciences), Vincent Dupriez (PerkinElmer)
This application note discusses how the Alpha SureFire® Ultra™ Multiplex technology provides a phosphoprotein multiplexing detection platform that is truly homogeneous and high throughput.
Case Study: Characterisation of hiPSCs by Phenotypic Screening
8 March 2018 | By PerkinElmer
Case study detailing a simple, highly reproducible phenotypic screen to characterise human induced pluripotent stem cells...
Application Note: Alpha Terbium SureFire Ultra Multiplex: simultaneous dual phosphoprotein target analysis
8 March 2018 | By PerkinElmer
In this application note, PerkinElmer demonstrates the measurement of two phosphoprotein targets in a single sample using the Alpha Terbium SureFire Ultra kit combined with the AlphaLISA SureFire Ultra kit...
Application Note: Fluorescence Polarization based assay for rapid, precise, high-throughput measurement of IgG & Fc containing derivatives
9 February 2018 | By BMG Labtech GmbH
The accurate, rapid and high-throughput measurement of IgG is essential in the development and manufacture of most therapeutic antibodies...
Application note: Simultaneous detection of GPCR second messengers in living cells
29 January 2018 | By BMG Labtech GmbH, Montana Molecular
Due to their role in signal transmission from the outside to the inside of a cell, G-protein coupled receptors are prominent drug targets...
Whitepaper: Phenotypic drug discovery with high content screening
25 January 2018 | By Jacob Tesdorpf (PerkinElmer), Josh P. Roberts (Lansdale)
Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.
Application note: Distinguishing cell types by phenotypic profiling
24 January 2018 | By Alexander Schreiner (PerkinElmer), Karin Böttcher (PerkinElmer), Mandy Malle (PerkinElmer)
Describing how a single nuclear stain can enable phenotypic profiling for new and additional perspectives on assays at no extra cost.
Tech note: Benefits of water immersion lenses for HCS
23 January 2018 | By PerkinElmer
Water immersion lenses provide: brighter images from HCS samples; faster and gentler imaging; higher quality images from both 2D and 3D samples.
Poster: Expansion of human induced pluripotent stem cells in scalable stirred suspension culture
12 January 2018 | By MilliporeSigma
Expansion of hiPSCs as aggregates in stirred suspension...
Poster: Expansion of human induced pluripotent stem cells in scalable stirred suspension culture
12 January 2018 | By Merck
Expansion of hiPSCs as aggregates in stirred suspension...
Application note: Functional GPCR studies using AlphaScreen cAMP Detection Kit
5 January 2018 | By Dawn Nida (PerkinElmer), Jen Carlstrom (PerkinElmer)
In this application note, PerkinElmer demonstrates the ease and utility of the AlphaScreen® cAMP assay for detecting both agonist and antagonist-induced cAMP responses within cells.
Application note: LANCE Ultra TR-FRET – based detection and modulation of Phosphorylated STAT3 levels in human cells
5 January 2018 | By Dawn Nida (PerkinElmer), Jen Carlstrom (PerkinElmer)
In this application note, PerkinElmer demonstrates how LANCE® Ultra, a homogeneous assay format, can be used to quickly and accurately assess modulation of pSTAT3.
Application note: Fc-Receptor binding in ADCC assays utilising LANCE Ultra Technology – characterisation of hIGs and FcγRIIIa
4 January 2018 | By Daniel Cardillo (PerkinElmer), Hong Cao (PerkinElmer), Stephen Hurt (PerkinElmer)
In this application note, PerkinElmer demonstrates the ease and utility of using LANCE® Ultra, a homogeneous assay format, for determining binding profiles of therapeutic monoclonal antibodies to FcγRs.
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