In an effort to address some of the more serious untreatable infections encountered by patients with cystic fibrosis, Calibr will collaborate with the Cystic Fibrosis Foundation on a two-year project.
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A new study has revealed that the Siah2 protein is crucial to control Tregs in mice, which can reduce the effectiveness of immunotherapies.
Scientists have found that when two specific genes are deleted in benign tumour tissue in the intestines, it more rapidly develops into a tumour that is more likely to become cancerous.
Scientists have used nanotechnology to transform healthy immune cells into a drug with enhanced power to kill bacteria to help the immune system fight sepsis.
The two organisations have entered into a two-year alliance to improve scientific exchange in the drug discovery industry.
A new drug-like compound has been developed which reportedly prevents the body from producing a protein that is often at the root of Parkinson's disease.
Researchers have utilised cryo-electron microscopy and used the images they captured with an electron microscope to generate atomic resolution models of the INTEGRATE system.
Drug Target Review lists its 10 most popular news stories from 2019, summarising the drug targets that you wanted to read about.
Researchers in New York have identified novel genes associated with the severity of peanut allergies and noted how these genes interact with other genes during allergic reactions. The findings could lead to better treatments for peanut allergies.
A survey has shown that the pharmaceutical industry believes R&D will see a lot of benefit from digital transformation and that AI will be at the forefront.
This issue includes a discussion on the future of high-throughput screening through collaboration, an analysis of mass spectrometry as a structural biology tool and an exploration of the challenges of hit-to-lead when researching tropical diseases. Also in the issue are articles on immuno-oncology and assays.