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Researchers image structure of cancer metastasis target
The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.
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Cyclisation reaction enables screening of macrocyclic compounds libraries
Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.
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Osteoporosis in mice reversed with new drug target
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
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Optofluidic chip platform developed for single molecule analysis
A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.
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Applying AI language translation to the creation of new pharmaceuticals
Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.
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Anti-viral immune discovery could lead to improved vaccines
A molecular switch that impacts immune responses to viral infections has been identified which could lead to better strategies to develop vaccines.
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Molecular Devices introduces the FLIPR® Penta system
Molecular Devices, LLC, today announced the launch of the next generation of its FLIPR® Penta High-Throughput Cellular Screening System.
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New discovery could lead to new treatments for Parkinson’s
New discovery makes it possible to design new therapies to replace alpha-synuclein's function in people with Parkinson's disease.
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Study shows p38 protein regulates formation of new blood vessels
A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.
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Gene differences that impact response to Cryptococcus identified
Using human data, a new study has examined how Cryptococcus genes impact patients with Cryptococcus Neoformans.
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Chemical synthesis and biological screening combined on chip
Researchers have developed a chip which facilitates and accelerates active substance production, characterisation and biological effectiveness.
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Light-stimulated brain cells could aid in stroke recovery research
A new 'optochemogenetics' research approach from scientists at the Emory University School of Medicine could aid in helping stroke victims.
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Job cuts limit cardiovascular and diabetes research and development
Pharmaceutical company, Sanofi, will eliminate jobs in France and Germany and end new in-house cardiology research programmes.
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Scientists have discovered important redundancies in T cells
Redundancies have been discovered in the biochemical signalling pathways of immune cells which could impact cancer immunotherapy.
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Protective antibodies identified that could be key to malaria vaccine
A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.