In-depth research maps virulence factor of the influenza A virus in real time
21 May 2019 | By Drug Target Review
Findings from a recent study could lead to the development of therapeutic approaches against influenza A viruses.
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Novel findings could improve vaccinations against STIs
20 May 2019 | By Drug Target Review
Researchers have shown how skin vaccinations could be used as a vaccination strategy for sexually transmitted infections (STIs).
Researchers take a leap forward for new anti-inflammatory drugs
13 May 2019 | By Drug Target Review
Treatments for chronic inflammatory diseases are one step closer as a new study discovers a way to stop inflammation in its tracks.
New study finally explains the link between inflammation and gastric cancer
17 April 2019 | By Drug Target Review
Researchers have finally shown how inflammation caused by H. pylori infection causes the proliferation of gastric epithelial stem cells, leading to gastric tumours.
Transforming drug discovery, development and delivery with flow chemistry
11 April 2019 | By Dr Omar Jina - Syrris Ltd, Prof Nicola Tirelli - Italian Institute of Technology Central Research Lab Genova
Flow chemistry is on the rise thanks to the commercial availability of benchtop continuous flow systems that has driven widespread adoption of the technique across a broad range of applications in both academia and industry. In particular, flow chemistry is delivering significant benefits in the area of drug discovery and…
Kick-starting the immune response – the shifting landscape of immuno-oncology
29 March 2019 | By Cisbio Bioassays, Nathan Robertson
The landscape of cancer treatment has changed dramatically in the last seven years, beginning with the approval of Ipilmumab in 2011, the first immunotherapy drug. Efforts to unsheathe the tumour cells of their protective microenvironment and expose them to an active immune response have delivered several monoclonal antibodies (mAbs) that…
Fast molecular interaction screening for all your projects
21 March 2019 | By NanoTemper Technologies
Current technologies that measure molecular interactions for drug discovery slow down and complicate screening. Dianthus is the answer to the demands for fast, non-stop, highly sensitive hit identification, hit validation and lead optimisation.
Cell line development – global market drivers, trends and its impact on improving biologics development from early phase to IND during the drug discovery process
19 March 2019 | By Aparajita Dubey - Associate Consultant at Prescient Healthcare Group
Cell line development is a major step for examining the efficiency of drug discovery, toxicity and in vitro testing. It reduces time, effort and cost, which minimises the chance of research drugs failing at the clinical trial stage. This stage involves the production of recombinant proteins such as monoclonal antibodies,…
Ticagrelor reversal agent provides immediate and sustained relief
18 March 2019 | By Drug Target Review
A reversal agent that sustains immediate relief from the side effects of ticagrelor stopping major bleeding, such as gastrointestinal hemorrhage...
Drug Target Review Issue 1 2019
14 March 2019 | By Drug Target Review
In this issue: AI-driven automated chemistry as a tool to accelerate drug discovery processes, the shifting landscape of immuno-oncology, and how lipid molecules provide an insight into biological research.
Potential EBV-associated cancer treatment in small molecule inhibitors
7 March 2019 | By Iqra Farooq (Drug Target Review)
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
Custom-made proteins create antibodies to fight HIV
27 February 2019 | By Drug Target Review
Computational modelling has been used to design proteins that mimic the conserved protein surface of different strains of HIV for use in vaccines...
Light-based production of drug discovery molecules
20 February 2019 | By Drug Target Review
Researchers have developed a method of using photocathodes and photoanodes to catalyse reactions that turn organic molecules into drug discovery ones...
Reversible antiplatelet therapy fights cancer metastasis and clotting
14 February 2019 | By Iqra Farooq (Drug Target Review)
A novel antiplatelet therapy could help to prevent heart attacks and stroke through preventing the formation of blood clots...
Protection against Mayaro virus using engineered DNA vaccine
8 February 2019 | By Drug Target Review
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
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