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Mobile phase optimisation for oligonucleotide analytical methods by LC-MS

ON-DEMAND By Phenomenex

In this on-demand, we provide an overview of nucleic acid therapeutics and discuss the chromatographic challenges associated with oligonucleotides. We also explore modulation of the mobile phase additives alkylamine ion pair and perfluorinated alcohols. Finally, we will show how optimisation of mobile phase can improve not only chromatographic performance and…

Cell-based Surface Plasmon Resonance with AstraZeneca

ON-DEMAND By Biosensing Instrument

In this webinar, we will provide an overview of the technology with some application examples and also see a case study how AstraZeneca is exploring SPRM for studies on G-protein-coupled receptors (GPCR) in close collaboration with Biosensing Instrument.

New horizons in small molecule solubility screening

ON-DEMAND By Halo Labs

Aqueous solubility of small molecule compounds is an essential parameter during the hit-to-lead stage of drug discovery as well as lead optimization and formulation. Low solubility can result in misleading ADMET/DMPK analyses if some fraction of a compound precipitates. Watch on-demand to find out more!

Measuring the affinity of challenging protein targets

ON-DEMAND By Fluidic Analytics

Join us as we discuss the latest data from the literature and application studies where diffusional sizing (MDS) is used to assess a variety of protein interactions – even of difficult targets.