Researchers have found that inherited mutations in the MINAR2 gene causes deafness. The findings suggest that deafness could be treated with genetic therapies.
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A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.
Viral vectors to deliver gene therapies are utilised by clinically approved therapies. However, this method is not the only option for advanced therapeutics. In this piece, Brent Warner, President, Gene Therapy at Poseida Therapeutics, discusses the balance between efficacy and safety in gene therapy, highlighting positive pre-clinical data for non-viral…
Here Bio-Rad presents the generation of specific anti-CAR T-cell antibodies to show how CAR T-cell analysis benefits from our modular antibody assembly technology using SpyTag-SpyCatcher protein ligation.
This podcast features an exploration of detecting host cell residual DNA in AAV vector production for gene therapy.
In this issue are articles focusing on a novel stem cell therapy for hearing loss, how a non-linear chiroptical effect could aid drug discovery and the advantages of cryo-electron tomography for imaging research. Also included are pieces on gene therapy, spheroids and genomics.
The new study highlights 11 genes which could be considered as potential candidates for novel therapeutics for type 1 diabetes.
Podcast discussion featuring CAR-T Cell therapy development and reviewing current challenges and future potentials for these cell therapies.
Hear from leading industry experts in this emerging field who discuss: challenges related to antigen and adjuvant selection, vaccine design, immune response improvement and future treatment options.
In their latest study, researchers at Moffitt Cancer Center have shown that cancer cells in an acidic environment undergo lipid synthesis and accumulation.
Find out more about the CAR-T cell therapy workflow in this informative infographic from Bio-Rad Laboratories (CA, USA). Discover some of the challenges associated with CAR-T cell R&D as well as technologies and reagents used for bioanalytical analysis.
Researchers have developed a promising new tool that accurately uses genomic data to predict disease risk across diverse populations.
Researchers have discovered that failed epigenetic suppression of an X-chromosome gene called Xist leads to miscarriage and developmental abnormalities.