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New technology system of drug-based markers for the selection or counter-selection of genes may advance genetic screening methods.
New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.
A novel gene therapy has fully corrected whole-body alterations in a rat model, paving the way for Morquio A therapies.
An NIH team have built a cellular map of chronic multiple sclerosis (MS) lesions to identify cells that drive inflammation and potential therapies.
The Gut Cell Atlas comprises 428,000 cells in the gut and sheds light on the origin of Crohn’s disease and other intestinal diseases.
An NIH study used whole-genome sequencing to describe three molecular subtypes of lung cancer in non-smokers, possibly improving treatments.
Stanford researchers have developed a multi-purpose “mini” CRISPR system, called CasMINI, that may be easier to deliver into human cells.
A genetic defect in patients with inflammatory bowel disease (IBD) was found to affect how intestinal epithelial cells maintain a barrier.
A new study has found mutations originating in blood progenitor cells, possibly leading to Waldenstrom macroglobulinemia (WM) therapies.
Scientists unveiled how a DNA repair protein may prevent Huntington’s disease, presenting a new target in future therapies.
Researchers have developed a novel algorithm, “scArches”, that can compare data on single-cell genomics to better understand diseases.
NPSR1 has been identified as a genetic cause of endometriosis, revealing a potential drug target that may lead to better therapies.
Dr Ronald G Crystal, Professor and Chairman of the Department of Genetic Medicine, Weill Cornell Medical College, spoke to Drug Target Review’s Victoria Rees about his research into Alzheimer’s disease and why gene therapies represent a promising area of research for neurodegenerative conditions.
Scientists have developed brain organoids that recapitulate the head size of autism patients to study the condition as well as possible therapies.