A mechanism has been identified which regulates the release of insulin from β-cells and could be used to develop new treatments for type 2 diabetes.
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A method designed to genetically alter laboratory mice can also be used to produce personalised animal models of an aggressive type of malignant brain cancer in children.
Researchers have discovered neurons send electrical signals to glioblastoma tumours, causing them to grow but have also identified methods of prevention in models.
A new target has been identified for the treatment of heart failure, heart attack, stroke and neurodegeneration.
A new platform combines AI, flow chemistry and robotics to minimise the need for human intervention in the synthesis process.
A study has revealed that the mitoNEET protein controls a metabolic and functional gateway on mitochondria, which could provide a drug target for cancer.
Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.
A study has shown that CRISPR can be used as a regenerative technique to treat Duchenne muscular dystrophy, which could be developed as a therapeutic option for humans.
Researchers have created a new technology which enabled them to discover more about the causes of Huntington’s disease and which can be used to test drugs.
The memory of mice with Alzheimer's greatly improved after they were injected with two newly discovered short peptides.
A new study has shown a new mechanism of controlling fat production in the body which could lead to new therapies to treat obesity.
A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.
Chronic inflammatory processes in ageing brains lead to lymphoma cells that have entered the brain tissue being retained.
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.