Targeting RAS to overcome FLT3 AML drug resistance
It was discovered that targeting RAS proteins prevent cancer cells from using different signalling pathways to escape cell death.
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It was discovered that targeting RAS proteins prevent cancer cells from using different signalling pathways to escape cell death.
Researchers find the mechanism which may underly the onset and progression of age-related neurodegenerative diseases.
The new study found T3s treatment exhibited neuroprotective effects in HFSD-fed mice by mitigating oxidative stress.
The move to Cambridge Innovation Park reflects the continued growth of Zyme's internal team and client network.
The new films killed over 80 percent of cancer cells, reduced recurrence rates and minimised undesirable chemotherapy side effects.
Researchers have developed a new tool called ‘Uveal Melanoma Immunogenic Score’ to predict which patients will respond to adoptive therapy.
A urine-based test that detects ctDNA from HPV-positive head and neck cancers could facilitate its early detection.
Researchers have identified that gestational diabetes is associated with a deficit in placental expression of IGFBP1.
The new findings could result in a clinical trial to assess whether a one-year course of treatment could stop brain tumours.
The new findings could lead to new therapeutics and a method to diagnose pancreatic cancer earlier, improving its prognosis.
The discovery that genomic deletions cause altBRAFs can help develop new therapies to overcome drug resistance in BRAF-mutant melanoma.
The discovery of three m6A modifications and their exact locations could lead to the development of drugs that inhibit viral RNA and protein production.
Evidence indicating that FOXO1 plays a unique role in promoting T cell longevity could result in more effective CAR T cell therapies.
Mutation signatures and recurrent copy number alterations correlated with a higher risk for disease progression.
Elevated levels of trimethylamine N-oxide levels were a stronger indicator of CKD risk than the well-known risk factors.