List view / Grid view
19 March 2019 | By Drug Target Review
The epigenetic protein, EZH2, was found to delay the development of acute myeloid leukemia (AML) but also switches sides to maintain tumour growth...
18 March 2019 | By Drug Target Review
A reversal agent that sustains immediate relief from the side effects of ticagrelor stopping major bleeding, such as gastrointestinal hemorrhage...
15 March 2019 | By Drug Target Review
Researchers have found that the enzyme USP15 could potentially lead to new therapies for both breast and pancreatic cancer...
14 March 2019 | By Drug Target Review
In this issue: AI-driven automated chemistry as a tool to accelerate drug discovery processes, the shifting landscape of immuno-oncology, and how lipid molecules provide an insight into biological research.
14 March 2019 | By Iqra Farooq (Drug Target Review)
A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
7 March 2019 | By Iqra Farooq (Drug Target Review)
A small molecule inhibitor has been observed to activate a dramatic reduction in tumour growth in EBV-associated tumours...
6 March 2019 | By Iqra Farooq (Drug Target Review)
Gene partnerships found in salamander could give insights into how spinal cord injuries and neurodegenerative conditions could be better treated...
5 March 2019 | By Iqra Farooq (Drug Target Review)
Researchers have repurposed use of niclosamide to treat Helicobacter pylori cell lines, focusing on how it is effective in infection models...
4 March 2019 | By Nic Losardo (Drug Target Review)
Genomics could be used to match drugs to patients better, with these genetic signatures also giving an earlier insight into detection of the condition...
1 March 2019 | By Iqra Farooq (Drug Target Review)
A meta-analyses of a number of studies has found that variants in numerous genes work together to contribute to Tourette's syndrome...
28 February 2019 | By Nic Losardo (Drug Target Review)
Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer...
27 February 2019 | By Iqra Farooq (Drug Target Review)
Engineered T-cells that target NFAT and Nr4a proteins could help to prevent the exhaustion of T-cells during CAR-T immunotherapy...
27 February 2019 | By Drug Target Review
Computational modelling has been used to design proteins that mimic the conserved protein surface of different strains of HIV for use in vaccines...
26 February 2019 | By Drug Target Review
Antimicrobial peptides were found to act against Gram-negative bacteria and certain fungi by working either together or by adding up their individual effects...
25 February 2019 | By Iqra Farooq (Drug Target Review)
Researchers have identified the mechanism by which highly toxic compounds communicate, and how they use vesicles to be transported...
Follow: