Using X-ray crystallography and cryo-electron microscopy, researchers have elucidated the structure of the SARM1 protein, a target for neurodegeneration.
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A team of researchers have used microscopy techniques to monitor DNA degradation and anticancer drug release from nanostructures.
Researchers have developed a new technique called mim-tRNAseq to measure, map and analyse tRNAs in cells, providing insight into disease.
A fluorescence imaging technique has allowed scientists to observe RNA in real time using single-molecule localisation microscopy.
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Researchers have found that the S1/S2 cleavage of the SARS-CoV-2 Spike protein could be a potential target for COVID-19 therapeutics.
Using liquid chromatography/mass spectrometry, researchers have revealed no major differences in glycan structures in two prion strains.
Using single-cell RNA sequencing, researchers have shown that interferon response is correlated with tuberculosis progression.
Comparing the original SARS-CoV-2 Spike protein with a mutated version, researchers have potentially revealed why the mutated version is dominant.
The N439K mutation improves the interaction between SARS-CoV-2 Spike protein and the viral receptor ACE2 and eludes antibody-mediated immunity, say investigators.
Learn how Simple Western automated immunoassays screen degraders and IMiD compounds to quantify degradation activity, providing accurate DC50 and Dmax values.