HD vein imaging aids intravenous injections
7 September 2018 | By Iqra Farooq (Drug Target Review)
Near-infrared light can now be used to aid clinicians in identifying veins in patients, especially when this process becomes difficult...
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Imaging
Transparent high-resolution EEG array allows brain imaging
7 September 2018 | By Drug Target Review
Researchers have developed a see-through, dual-layered, mesh EEG device which is capable of measuring the electrical activity of individual neurons...
Nuclear PET imaging method developed for tumour detection
6 September 2018 | By Iqra Farooq (Drug Target Review)
Researchers have developed a PET imaging method suitable for many forms of cancer, with high contrast and less inconvenience to patients...
Expert view: New developments in real‑time live‑cell analysis
5 September 2018 | By Del Trezise
Live-cell analysis is now a well-established method that is part of the everyday cell biologist’s armoury for understanding cell biology. For over a decade, the functionality, throughput, and ease of use offered by real-time live-cell analysis has provided a platform for accurate and reproducible cell biology analysis in multiple biomedical…
Making an early link between cognitive impairment and Alzheimer’s
5 September 2018 | By Drug Target Review
Researchers in the U.S. have devised a novel strategy to effectively identify those individuals with mild cognitive impairment that will most likely go on to develop Alzheimer's disease.
Drug Target Review – Issue 3 2018
3 September 2018 | By Drug Target Review
In this issue: pharmacological targeting of mitochondrial dysfunction in Parkinson’s disease, the evolving role of three dimensional in-vitro cell culture techniques in drug discovery, and NGS: hunting mysterious ‘Dark Matter Genome’ towards rewriting the rules of genetic diseases.
Scientists develop TSA-Seq technique for precise 3D mapping of human genome
29 August 2018 | By Drug Target Review
Despite the human genome being first sequenced almost 20 years ago, researchers know comparatively little about how the genome is organised within cells. But a new TSA-Seq technique is changing that.
Novel imaging biomarker to help predict coronary inflammation
29 August 2018 | By Drug Target Review
Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality...
Novel PET imaging could guide therapy for type 1 diabetes
6 August 2018 | By Drug Target Review
Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...
Aortic plaques may contribute to liver disease progression
3 August 2018 | By Drug Target Review
Aortic atherosclerotic plaque inflammation may contribute to the progression of non-alcoholic fatty liver disease to liver fibrosis...
Exploring horizons in 3D microscopy: what the future holds
25 July 2018 | By Dimitri Scholz (University College Dublin), Karl Gaff (Dublin Institute of Technology)
The microscope slide is flat (2D), but the world around us is not – despite the flat-earth theories. We need volume information about our samples, ideally with high resolution in all three dimensions as well as over time – the fourth dimension...
Applications of molecular imaging in drug development
25 July 2018 | By Ben Burke (University of Hull and Castle Hill Hospital), Steve Archibald (University of Hull and Castle Hill Hospital)
The world of healthcare is rapidly evolving. With an ageing population, comes a significant increase in cancers, metabolic diseases and neurodegenerative disorders. New drug candidates are required; however drug development remains a lengthy and expensive process, with the average timeline now over 10 years and costs continuing to rise...
32,000 images of analysed CT scans released for AI development
23 July 2018 | By Drug Target Review
Thousands of images have been released to encourage scientists to develop their analysis of lesions, advocating its use for the development of a new universal lesion detector...
New 3D ‘nanoscope’ facilitates improved brain imaging for Alzheimer’s research
17 July 2018 | By Drug Target Review
Scientists in the U.S. have developed a powerful imaging tool to more accurately reproduce visuals of the brain and investigate mechanisms that precede Alzheimer’s symptoms.
SPECT Imaging technique illuminates immune status of monkeys with HIV-like virus
16 July 2018 | By Dr Zara Kassam (Drug Target Review)
Approach could improve understanding of immune system recovery in people treated for HIV infection...
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