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STING-activating drugs could customise cancer treatments
An imaging technique identified emerging drugs that activate the STING protein to alter metabolic pathway activity in cancer cells.
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Imaging
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S1P may be a potential target for cerebral blood alterations
Sphingosine-1 phosphate was found to regulate blood glow in cerebral blood vessels in mice, presenting a potential therapeutic target.
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New precise method can visualise individual blood cells in the brain
Researchers have developed an inexpensive method for visualising blood flow in the brain that can discern the motions of individual blood cells.
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On-demand webinar: An AI-based approach to phenotypic characterisation of neuronal cells
Evaluation of neurotoxicity effects is an active area of investigation in drug discovery and disease modeling.
whitepaper
Whitepaper: Characterising astroglia models
This whitepaper describes several live-cell phenotypic analyses suitable for the characterisation of astroglia cells.
whitepaper
Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
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New exclusive report: AI & Informatics: Drug discovery and development
In this exclusive report, find an in-depth analysis of AI and informatics within imaging, synthetic biology, drug screening and drug design. Featured interviews with experts from AstraZeneca, Auransa, PolarisQB and Chalmers University of Technology.
whitepaper
Handbook: Latest edition live-cell analysis
The latest edition of the live-cell analysis handbook is a companion guide for live-cell analysis users. Includes discussion of live-cell analysis.
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Spatial genomic and transcriptomic imaging in drug discovery
In this interview, read about the compilation of a new high-resolution cell atlas of the mouse brain using spatial genomics and transcriptomics.
whitepaper
Application note: Measure viral-induced cytopathic effects with a quantitative luminescence assay
Depletion of ATP due to viral-induced CPE leads to a reduction in luminescence signal, enabling quantitation of viral-induced CPE in host cells.
news
Non-invasive optical method could provide insight into brain diseases
A non-invasive, label-free optical method can produce high-resolution imaging of cellular brain diseases in vivo.
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High-quality, rapid technique developed for imaging in vivo
A US team has designed a high-quality, high-speed imaging system that could lead to new understandings of complex tissue specimens.
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High-throughput method developed for single-cell metabolic profiling
Scientists have presented a new method for generating the metabolic profiles of cells which could answer questions on conditions such as cancer and liver disease.
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New microscopy method could lead to advancements in cell biology
Researchers at UT Southwestern have invented a novel microscopy method that could open new avenues of advanced microscopy.
whitepaper
ebook: Optimise your high value cell lines
As interest in biotherapeutic proteins grows, the need to reduce cell line development costs and the time to market is more critical than ever.