Researchers have produced a capillary model which allows investigation of the dynamics of blood flow obstruction in real scale and could be used to test new therapies for P. falciparum malaria.
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Using brain scans, a study has shown that schizophrenia patients have lower levels of the protein SV2A in their brains which presents a drug target.
A new study has developed a deep learning approach that analyses protein interactions, which could improve the design of drugs in the future.
Researchers have demonstrated the success of a new single-particle method of studying the surface of viruses, which could improve vaccine purification and the development of gene therapies.
A new study has used several imaging techniques to characterise C. diff toxins, which could help to design drugs to combat infections from the bacteria.
A new spectrometer laser system has been developed by researchers in Germany, which can detect specific compounds in biological samples.
Researchers have utilised cryo-electron microscopy and used the images they captured with an electron microscope to generate atomic resolution models of the INTEGRATE system.
A group of scientists from India have used 3D imaging of the Nipah virus to discover potential inhibitors for the disease.
Researchers have used ghost imaging to enhance the imaging speed of nanoscopy, which could make it possible to capture processes in living cells at speeds not previously possible.
Researchers have used a machine-learning algorithm to study protein appearance and discover common features that influence function, which could be used to design artificial cells.
This issue includes a discussion on the future of high-throughput screening through collaboration, an analysis of mass spectrometry as a structural biology tool and an exploration of the challenges of hit-to-lead when researching tropical diseases. Also in the issue are articles on immuno-oncology and assays.
A new mechanism has been reported for detecting foreign material during early immune responses which may help detect elusive cancers.
A study has demonstrated how mutations in early colon cancer prevail and grow into malignancies, using fluorescent imaging.
Get increased sensitivity for the detection of endotoxin in a fluorescence assay.