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Stem Cells In-Deth Focus 2020

26 May 2020 | By

The stem cells in-depth focus includes articles on using computational approaches expand the applications of stem-cell therapies and how organoids could be used to speed up the drug discovery process with a focus on retinal disease.

Imaging In-Depth Focus 2020

26 May 2020 | By

The articles in this in-depth focus discuss the difficulties in deciding what information to capture when imaging three-dimensional (3D) cell models and the use of non-invasive imaging techniques to discover small molecule drugs to control protein translation.

Immuno-oncology In-Depth Focus 2020

26 May 2020 | By

This in-depth focus features articles on using combinations of immuno-oncology drugs to target solid tumours and heamatological cancers, and how neoantigens of cancer cells could be used as the basis of novel immuno-oncology vaccines.

Screening In-Depth Focus 2020

26 May 2020 | By

Included in this in-depth focus are articles on how high-throughput screening can be used to identify lead compounds, using chemoinformatics as a map to guide drug discovery and a novel in vitro model to screen potential treatments for non-alcoholic fatty liver disease (NAFLD).

Drug Target Review – Issue 2 2020

26 May 2020 | By

In this issue authors discuss the development of COVID-19 antibody therapies, how high-throughput screening enhances research at the Crick Institute and why combinations of immuno-oncology drugs could revolutionise treatment of advanced cancers. Also included in the issue are articles on stem cells and imaging.