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Applications of molecular imaging in drug development

25 July 2018 | By ,

The world of healthcare is rapidly evolving. With an ageing population, comes a significant increase in cancers, metabolic diseases and neurodegenerative disorders. New drug candidates are required; however drug development remains a lengthy and expensive process, with the average timeline now over 10 years and costs continuing to rise...

Cancer drug screening: the historical perspective

20 July 2018 | By , , , ,

Chemotherapy with cytotoxic and growth inhibitory drugs have played an important role in cancer therapy, used either alone or in combination with other treatment modalities such as surgery, radiation or biological therapy. Chemotherapy, in most instances, was the only alternative treatment for metastatic cancer – mainly given as drug combinations...

From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research

20 July 2018 | By , ,

Mesenchymal stem cells (MSCs) are fibroblast-like cells that give rise to mesenchymal derivatives including bone, fat and cartilage cells. In addition to the bone marrow, they can be readily obtained from adult vascularised peripheral tissues including adipose, olfactory, respiratory tissue, and peripheral blood.

Urine-derived stem cells as innovative platform for drug testing and disease modelling

20 July 2018 | By , , , , , ,

Kidneys are crucial for filtration of drugs and toxins and their proper function is essential for overall health. Unfortunately, due to disease and improper function, kidney transplantation or dialysis are necessary for millions of patients annually all over the world.1,2

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