Application note

Application note: In situ identification of cancer stem cell niches (HCC)

Posted: 1 February 2024 | | No comments yet

This app note explores a groundbreaking multiplex immunodetection approach to identify cancer stem cell niches within hepatocellular carcinoma (HCC).

Explore the characterization of fibrous nest subtypes in HCC on cancer patients with poor overall survival, focusing on the in situ localization of extracellular matrix (ECM) signatures using Cell DIVE multiplex imaging.


  • How intratumoral structures are identified using proteomics
  • How to identify topographical tissue landmarks and ECM proteins
  • How to perform multiplexed immunohistochemical analyses
  • How to identify, label and analyze antibodies from immunostained tissue sample images

Click here to read now.

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