Application note: In situ identification of cancer stem cell niches (HCC)
Posted: 1 February 2024 | Leica Microsystems | No comments yet
This app note explores a groundbreaking multiplex immunodetection approach to identify cancer stem cell niches within hepatocellular carcinoma (HCC).
Explore the characterization of fibrous nest subtypes in HCC on cancer patients with poor overall survival, focusing on the in situ localization of extracellular matrix (ECM) signatures using Cell DIVE multiplex imaging.
Discover:
- How intratumoral structures are identified using proteomics
- How to identify topographical tissue landmarks and ECM proteins
- How to perform multiplexed immunohistochemical analyses
- How to identify, label and analyze antibodies from immunostained tissue sample images
Related topics
Antibodies, Biomarkers, Cancer research, Drug Discovery Processes, Drug Targets, Imaging, Immuno-oncology, Microscopy, Protein, Proteomics, Stem Cells
Related organisations
Leica Microsystems
