A gene associated with a rare balance disorder also regulates the behaviour of an enzyme that increases the risk for Alzheimer's disease.
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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.
A new study has used a combination of imaging methods to understand how the Piezo protein works, improving research into treatments for conditions such as high blood pressure.
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
A study has discovered the regulating process behind cell autophagy which could aid in the development of neurodegenerative disease treatments.
Researchers have found that the presence of microglia brain cells allowed plaques to form in the brains of rodents, leading to Alzheimer’s disease.
A study has revealed a drug target for skin cancers which regulates the differentiation of cells and the roles they conduct in the body.
Researchers have revealed a key inflammation mechanism that contributes to melanoma brain metastasis and could be a therapeutic target.
A study has discovered a pathway that allows the enterovirus to successfully infect cells and promote genome release which could be a therapeutic target.
Claus Bendtsen at AstraZeneca reveals how AI can be used to improve our understanding of disease, to help identify the causes of conditions and aid in drug discovery.
Researchers have discovered electrical channels important in sensory cell renewal which could be studied further to develop therapies for retinal diseases.
Researchers have created a fruit fly model to investigate uric acid-related diseases such as diabetes to aid in drug development.
Designing new drug molecules is crucial to R&D. Dr Sam Genway suggests that one way to improve and speed up this process is using AI inspired by language translation.
A study has discovered a molecule key in neuronal growth that could be used as a drug target to treat anxiety-related diseases.