In primate models, researchers have successfully shown that developed AAVs can cross the blood-brain barrier, which keeps many drugs from getting into the brain.
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A drug target is anything within a living organism to which a drug is directed and/or binds, resulting in a change in its behaviour or function.
Swedish researchers have discovered that by measuring immune cells in the cerebrospinal fluid when diagnosing ALS, it is possible to predict how fast the disease may progress.
A US researcher studied 3D structures of brain cells and connections, revealing new role for oligodendrocyte precursor cells (OPCs), in mice.
US researchers have tested mRNA-based vaccine against influenza viruses, with promising results in animal models, that pave the way for clinical trials.
Does treating adolescent acne with systemic antibiotics have unintended consequences on the skeleton?
US researchers unmask the consequences of treating adolescent acne with systemic antibiotics; as it can lead to altered profiles of circulating bile acids that reduce osteoblast function and bone mass accrual.
US researchers showed that the protein: GRP78, implicated in COVID-19 and cancers, is effected by the new drug HA15.
US researchers find that bacteria could help tumours progress and resist treatment.
US researchers have identified a protein that interacts and enhances the spread of neurotoxic species of tau, which is primarily found in neurons that appear abnormal in the brains of Alzheimer’s disease patients.
SK bioscience and IVI convened in consultative meeting to discuss cooperation for next pandemic and announced KRW3 billion donation to IVI to support advancement of global vaccine R&D
US researchers, using a 3D neural tissue model, found that compounds from green tea and resveratrol could diminish Alzheimer’s amyloid plaques in lab tests, with no side effects.
In this exclusive Q&A, Dr Robert Baldock, Research Scientist at the University of Portsmouth, discusses the compound hydroquinine and how it could be used as an effective weapon against a pathogen that causes serious infections in humans, mostly hospital patients.
German researchers have designed peptides that bind to amyloidogenic proteins linked to Alzheimer’s and type 2 diabetes, to effectively suppress both cytotoxic amyloid aggregation and amyloid cross-accelerating interactions.
Researchers have found that beer hop compounds can inhibit the clumping of proteins associated with Alzheimer's disease.