A new therapeutic route for combatting treatment-resistant cancer has been identified with the discovery that melanoma cells fight anti-cancer drugs by changing their internal skeleton.
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A new study has developed a deep learning approach that analyses protein interactions, which could improve the design of drugs in the future.
Central to reproducibility in biomedical research is the ability to use well-characterised and defined reagents. The CPTAC Antibody Portal serves as a National Cancer Institute community resource that provides access to many standardised renewable affinity reagents to cancer-associated targets and accompanying characterisation data. Nikki Withers spoke to Dr Tara Hiltke…
An unexpected finding about a protein that's highly expressed in fat tissue could lead to new approaches for addressing obesity and many other diseases.
Researchers have slowed the spread of a type of non-small cell lung cancer in mice by neutralising a protein that would otherwise cause tumour growth.
The involvement of clathrin in the development of liver cancer has been described for the first time, which could lead to more targeted therapy.
A study has used a proteomic method to uncover why some melanoma tumours do not respond to immunotherapy, which could improve treatments.
A protein that causes pancreatic ductal adenocarcinoma has been identified as a therapeutic target by researchers.
A research team have found a signalling pathway which plays a critical role in the maturation of periodontal ligament, providing information for the development of dental treatments.
A new technique called ‘ubiquitin clipping’ has been created which could aid proteomics research and the development of new drugs for ubiquitination.
A machine-learning model has been developed to analyse protein sequences, giving an insight to their structure, function and phylogeny...
Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia...
Researchers have developed the first viable mouse model of Hirschsprung’s disease and associated enterocolitis with a defect in GDNF/GFRa1/RET signalling...
Proteomics research has become a popular method for characterising functional proteins as well as discovering the innovative targets for oncologic disorders...