Poster: Assays for PRMT5, MLL4, METTL3/14, & NSP14

AptaFluor SAH: A Homogenous, Universal Assay for Histone, RNA, & DNA Methyltransferases. Case Study for PRMT5, MLL4, METTL3/14, & NSP14

The AptaFluor SAH assay is a reliable and robust tool for detecting the activity of methyltransferases using various acceptor substrates, including peptides, DNA, and RNA. Selected enzymes are representative of typical low KM (100 nM to 5 µM) and have attracted interest as therapeutic targets. The poster describes using the assay to discover novel methyltransferase inhibitors as potential therapeutics for disease.

Interested? Register your details to access this exclusive content