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Faster drug discovery could hit ‘undruggable’ targets
A new technique has been developed which has the potential to harness bacteria to produce billions of different drug candidates to treat diseases like cancer.
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Drug Discovery Processes
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Expert view: The future of cell expansion for monoclonal antibody production
There is room for improvement in the production of monoclonal antibodies; commercial production needs increased process efficiency and reduced costs.
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Expert view – The Octet HTX system: enabling multi-purpose screening of therapeutic biologics during development
Current trends in the development of therapeutic biologics suggest that engineered molecules such as bispecific antibodies and antibody-drug conjugates are the future of the industry, yet despite this, monoclonal antibody (mAb) development remains a dominant focus.
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Fungi library could aid in the search for medical drugs
A library of products derived from more than 10,000 fungi has been established which could lead to the discovery of new drugs.
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AI in drug discovery market to increase at CAGR of 40.8 percent
Research has found that artificial intelligence in drug discovery will be worth $1,434 million by the end of 2024.
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ELRIG Drug Discovery 2019: looking back to the future
On 5-6 November, ACC Liverpool hosted the ELRIG Drug Discovery event, which allowed R&D professionals to come together and discuss the latest industry developments.
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Application note: Reliable Single Cell Cloning with Advanced Microfluidic Dispensing
Find out how to accelerate and improve selective single cell cloning with advanced microfluidic dispensing.
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Machine-learning algorithm developed to aid in epigenetic drug discovery
A machine-learning algorithm has been created that automates high-throughput screens of epigenetic medicines.
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Platform may find new options for mental health treatment
A drug discovery platform for mental health treatment could also help to identify mechanisms for the treatment of substance use disorders.
whitepaper
Application note: Automated imaging of cell viability
Automated fluorescence imaging and quantification of cell viability, with EVOS cell imaging system
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A biosynthetic pathway to identify new drug candidates
A new process for identifying and biosynthesising drug candidates has been discovered by researchers at the Carl R Woese Institute for Genomic Biology.
whitepaper
Application note: High-throughput imaging and analysis of spheroids
High-throughput fluorescence imaging and analysis of spheroids - tips, tricks, and tools to efficiently grow, stain, image, and analyze 3D cell cultures
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Integrating drug discovery R&D
Pharmaceutical companies are under increasing pressure to get novel drugs to market as quickly as possible. Here, Sheraz Gul discusses how integrating processes could help streamline drug discovery in the future.
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New strategy developed to speed up drug discovery process
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
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AI designed, synthesised and validated new drug in 46 days
Researchers have developed a new AI system which was able to discover and then successfully test several new compounds within 46 days.