A study has shown that CRISPR can be used as a regenerative technique to treat Duchenne muscular dystrophy, which could be developed as a therapeutic option for humans.
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Stem cells are undifferentiated biological cells that can differentiate into specialised cells and can divide to produce more stem cells.
CRISPR is the buzzword of the moment in the drug discovery industry – mainly due to its potential to correct disease-causing mutations. However, those using the technology need to be mindful that it is used responsibly, and possible risks are considered before use. Mark Behlke discusses the potential of CRISPR…
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
Application note: Multiplexed automated imaging assay for cardiotoxic compounds using the ImageXpress Pico system
There is an increasing need to expand the variety and complexity of cell-based assays for biologic research and drug discovery.
A ground-breaking nervous system discovery could be significant for the treatment of different neurological diseases.
A potential target for ALS has been revealed by a study which found the Fos-B gene encouraged axonal branching.
Scientists combine organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research.
It has been discovered that Id4 controls whether stem cells enter cell division and may be relevant for treating neurodegenerative disease.
Combining organoid and organ-on-a-chip technologies, researchers have created a model which will allow them to study eye diseases and treatments for the retina.
A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.
A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.
Researchers may have fundamentally altered the way scientists study brain diseases with new CRISPR technology.