The guide provides examples of how Transcreener allowed rapid assay development to enable screening for kinases in innate immune pathways.
Clinical trials continue to determine whether therapeutic modulation of kinases can be used to suppress the immune system in autoimmune diseases or stimulate for antiviral and cancer immunotherapy. The discovery and characterization of small molecule modulators have aided these efforts. This article provides five examples of how Transcreener allowed rapid assay development to enable screening and dose-response measurements for kinases in these pathways.
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Kinases and innate immunity
Using biochemical assays to interrogate kinases for small molecule discovery
Assay flexibility
IRAK4
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