Why PARP inhibitors fail: key role of the CST complex in BRCA1-deficient cancers

By 2025-06-27T13:30:34

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Researchers from UT Health San Antonio have identified the CST protein complex as a key driver of resistance to PARP inhibitors in BRCA1-deficient cancers – which could lead to more personalised treatments for breast, ovarian and prostate cancer patients.

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