Drug Target Review Immuno-oncology ebook 2022

Included in this ebook are articles on how to develop more effective CAR T cells by modifying the CAR design and why recent findings about ferroptosis in cancer cells could enhance immunotherapies.

CAR T cells and immunotherapy have shown incredible promise at treating patients in the clinic, but there is still room for improvement of these approaches. In this ebook, Dr Sarwish Rafiq, Emory University School of Medicine, explores why real-time methods for assessing immune cell potency could aid the development of more effective CAR T cells.

Also included is an exclusive interview with Dr Weiping Zou from the University of Michigan Rogel Cancer Center, who describes a recent study he led which revealed how a cytokine and fatty acid work together to trigger ferroptosis in cancer cells. According to the researchers, these findings could be used to enhance immunotherapies.

Included in this ebook:

  • How to develop the next generation of CAR T-cell therapies
    Dr Sarwish Rafiq, Emory University
  • Triggering ferroptosis in cancer cells
    Dr Weiping Zou, University of Michigan