List view / Grid view

Dr Nilay Chakraborty

 

article

Making cell culture models more physiologically relevant

A major limitation in drug development is the occurrence of…

22 June 2021 | By

A major limitation in drug development is the occurrence of drug-candidate toxicity during clinical research. This may occur because tumour-derived cell lines are limited as a pre-clinical model – in part because of an altered metabolic poise. A recent study has revealed a profound plasticity in gene expression and metabolic poise that can…