Cell signalling through the Akt pathway controls numerous key cellular functions including proliferation, survival, and migration.
The ability to measure real-time Akt activation in living cells will provide valuable information on the involvement of Akt across multiple fields of research including oncology, neuroscience and inflammatory disease research. This application note includes detail on cell signalling through the Akt pathway, profiling Akt activity response to inhibitors and a focus on growth factors.
You will learn:
Assay principle and quantification
Direct and indirect inhibition of Akt
Targeting upstream regulators of Akt activity
Regulation of Akt activity in inflammation response
Akt activity regulates cell function.
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