4basebio PLC

4basebio is a Cambridge-based biotechnology company providing innovative technologies and products for gene therapy and vaccine development. Our enzymatic DNA synthesis platform allows for the GMP production of DNA products at unparalleled speed, scale, and purity as compared to pDNA. The proprietary DNA products have application specific benefits and feed into the production of mRNA, viral vectors, gene editing applications and DNA vaccine technologies. 4basebio’s non-viral delivery platform, Hermes™, confers enhanced stability over conventional LNP platforms, and is suitable for a range of nucleic acid and biological payloads, including synthetic DNA. Together, these platform technologies can greatly accelerate the development of gene therapy and vaccine programmes.

Streamlining Biomanufacturing of Personalised Cancer Immunotherapies with Synthetic DNA