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A scientist uses a pipette over a petri dish with digital molecular and chemical structure graphics, representing innovation and predictive modelling in drug discovery.
A scientist uses a pipette over a petri dish with digital molecular and chemical structure graphics, representing innovation and predictive modelling in drug discovery.
article

The predictive validity crisis: Pharma’s productivity paradox – Part II

24 October 2025 | By ,

Part II shows that the predictive validity crisis can be solved by rethinking how the industry chooses models, measures outcomes and integrates systems. Success stories from Vertex, Regeneron and AstraZeneca illustrate how aligning biology, measurement and strategy can reverse decades of declining productivity.